Mechanical thrombectomy in pediatric acute ischemic stroke: Clinical outcomes and literature review

Thomas P Madaelil; Akash P Kansagra; DeWitte T Cross; Christopher J Moran; Colin P Derdeyn

doi:10.1177/1591019916637342

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Mechanical thrombectomy in pediatric acute ischemic stroke: Clinical outcomes and literature review

Journal article

Open access

Peer reviewed

Mechanical thrombectomy in pediatric acute ischemic stroke: Clinical outcomes and literature review

Thomas P Madaelil, Akash P Kansagra, DeWitte T Cross, Christopher J Moran and Colin P Derdeyn

Interventional neuroradiology, Vol.22(4), pp.426-431

08/2016

DOI: 10.1177/1591019916637342

PMCID: PMC4984382

PMID: 26945589

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Abstract

There are limited data on outcomes of mechanical thrombectomy for pediatric stroke using modern devices. In this study, we report two cases of pediatric acute ischemic stroke treated with mechanical thrombectomy, both with good angiographic result (TICI 3) and clinical outcome (no neurological deficits at 90 days). In addition, we conducted a literature review of all previously reported cases describing the use of modern thrombectomy devices. Including our two cases, the aggregate rate of partial or complete vessel recanalization was 100% (22/22), and the aggregate rate of favorable clinical outcome was 91% (20/22). This preliminary evidence suggests that mechanical thrombectomy with modern devices may be a safe and effective treatment option in pediatric patients with acute ischemic stroke.

Mechanical Thrombolysis - methods

Stroke - surgery

Child

Humans

Brain Ischemia - surgery

Details

Title: Subtitle: Mechanical thrombectomy in pediatric acute ischemic stroke: Clinical outcomes and literature review
Creators: Thomas P Madaelil - Department of Neuroradiology, Mallinckrodt Institute of Radiology, USA madaelilt@mir.wustl.edu
Akash P Kansagra - Department of Neuroradiology, Mallinckrodt Institute of Radiology, USA
DeWitte T Cross - Department of Neuroradiology, Mallinckrodt Institute of Radiology, USA Department of Neurological Surgery, Washington University School of Medicine, USA
Christopher J Moran - Department of Neuroradiology, Mallinckrodt Institute of Radiology, USA Department of Neurological Surgery, Washington University School of Medicine, USA
Colin P Derdeyn - Department of Radiology, University of Iowa Hospitals and Clinics, USA Department of Neurological Surgery, University of Iowa Hospitals and Clinics, USA Department of Neurology, University of Iowa Hospitals and Clinics, USA
Resource Type: Journal article
Publication Details: Interventional neuroradiology, Vol.22(4), pp.426-431
DOI: 10.1177/1591019916637342
PMID: 26945589
PMCID: PMC4984382
NLM abbreviation: Interv Neuroradiol
ISSN: 1591-0199
eISSN: 2385-2011
Publisher: United States
Language: English
Date published: 08/2016
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984014883702771

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