Journal article
Mechanisms of Disease of Eosinophilic Esophagitis
Annual review of pathology, Vol.11(1), pp.365-393
05/23/2016
DOI: 10.1146/annurev-pathol-012615-044241
PMCID: PMC4918086
PMID: 26925500
Abstract
Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of EoE is now being elucidated, and food hypersensitivity is emerging as the central cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current clinical, pathologic, and molecular understanding of the disease with a focus on disease mechanisms.
Details
- Title: Subtitle
- Mechanisms of Disease of Eosinophilic Esophagitis
- Creators
- Benjamin P Davis - Division of Immunology, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242; email: ben-davis@uiowa.eduMarc E Rothenberg - Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229; email: rothenberg@cchmc.org
- Resource Type
- Journal article
- Publication Details
- Annual review of pathology, Vol.11(1), pp.365-393
- DOI
- 10.1146/annurev-pathol-012615-044241
- PMID
- 26925500
- PMCID
- PMC4918086
- NLM abbreviation
- Annu Rev Pathol
- ISSN
- 1553-4006
- eISSN
- 1553-4014
- Publisher
- Annual Reviews
- Grant note
- T32 HL007752 / NHLBI NIH HHS U19 AI070235 / NIAID NIH HHS R01 AI057803 / NIAID NIH HHS R01 DK067255 / NIDDK NIH HHS P30 DK078392 / NIDDK NIH HHS T32 AI060515 / NIAID NIH HHS R37 AI045898 / NIAID NIH HHS R01 AI080581 / NIAID NIH HHS U19 AI066738 / NIAID NIH HHS U54 AI117804 / NIAID NIH HHS R01 DK076893 / NIDDK NIH HHS
- Language
- English
- Date published
- 05/23/2016
- Academic Unit
- Stead Family Department of Pediatrics; Immunology; Internal Medicine
- Record Identifier
- 9984093326602771
Metrics
41 Record Views