Journal article
“Med-X”: a medical examiner surveillance model for bioterrorism and infectious disease mortality
Human pathology, Vol.38(5), pp.718-725
2007
DOI: 10.1016/j.humpath.2007.02.003
PMID: 17437862
Abstract
We created a model surveillance system (Med-X) designed to enable medical examiners and coroners to recognize fatal infections of public health importance and deaths due to bioterrorism. All individuals who died in New Mexico and fell under medical examiner jurisdiction between November 23, 2000, and November 22, 2002, were prospectively evaluated using sets of surveillance symptoms and autopsy-based pathologic syndromes. All infectious disease deaths were evaluated to identify the specific causative agent. Of 6104 jurisdictional cases, 250 (4.1%) met Med-X criteria, of which 141 (56.4%) had a target pathologic syndrome. Ultimately, 127 (51%) of the 250 cases were due to infections. The causative organism was identified for 103 (81%) of the infectious disease deaths, of which 60 (58.3%) were notifiable conditions in New Mexico. Flu-like symptoms, fever and respiratory symptoms, and encephalopathy or new-onset seizures had predictive values positive for fatal infections of 65%, 72%, and 50%, respectively, and are useful as autopsy performance criteria. Before the development of surveillance criteria, 37 (14.8%) of the cases ordinarily would not have been autopsied resulting in a 1% increase in autopsy workload. Med-X is an effective method of detecting infectious disease deaths among medical examiner cases. Uniform criteria for performing medical examiner autopsies and reporting cases to public health authorities enhance surveillance for notifiable infectious diseases and increase the likelihood of recognizing deaths related to bioterrorism.
Details
- Title: Subtitle
- “Med-X”: a medical examiner surveillance model for bioterrorism and infectious disease mortality
- Creators
- Kurt B Nolte - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USASarah L Lathrop - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USAMarcus B Nashelsky - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USAJeffrey S Nine - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USAMargaret M Gallaher - New Mexico Department of Health, Santa Fe, NM 87505, USAEdith T Umland - New Mexico Department of Health, Santa Fe, NM 87505, USAJerri L McLemore - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USAR. Ross Reichard - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USARebecca A Irvine - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USAPatricia J McFeeley - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USARoss E Zumwalt - Office of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USA
- Resource Type
- Journal article
- Publication Details
- Human pathology, Vol.38(5), pp.718-725
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.humpath.2007.02.003
- PMID
- 17437862
- ISSN
- 0046-8177
- eISSN
- 1532-8392
- Language
- English
- Date published
- 2007
- Academic Unit
- Epidemiology; Pathology
- Record Identifier
- 9984047776802771
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