Journal article
Media for colistin susceptibility testing does not improve the detection of Klebsiella pneumoniae isolates carrying MgrB disruption and other mutation driven colistin resistance mechanisms
Diagnostic microbiology and infectious disease, Vol.98(1), pp.115077-115077
09/2020
DOI: 10.1016/j.diagmicrobio.2020.115077
PMID: 32629337
Abstract
We evaluated different susceptibility testing media against 200 Klebsiella pneumoniae isolates that have been genetically characterized for the presence of polymyxin resistance mechanisms. The media evaluated included calcium enriched media that was described to promote separation of mcr-carrying Enterobacterales isolates and standard cation-adjusted Mueller-Hinton broth with and without polysorbate 80. The testing conditions evaluated did not show improvement in the separation of isolates carrying MgrB alterations and other mutation-driven polymyxin resistance mechanisms.
Details
- Title: Subtitle
- Media for colistin susceptibility testing does not improve the detection of Klebsiella pneumoniae isolates carrying MgrB disruption and other mutation driven colistin resistance mechanisms
- Creators
- Mariana Castanheira - JMI LaboratoriesTimothy B Doyle - JMI LaboratoriesCecilia G Carvalhaes - JMI LaboratoriesBrieanna M Roth - JMI LaboratoriesPaul R Rhomberg - JMI LaboratoriesRodrigo E Mendes - JMI Laboratories
- Resource Type
- Journal article
- Publication Details
- Diagnostic microbiology and infectious disease, Vol.98(1), pp.115077-115077
- DOI
- 10.1016/j.diagmicrobio.2020.115077
- PMID
- 32629337
- ISSN
- 0732-8893
- eISSN
- 1879-0070
- Language
- English
- Date published
- 09/2020
- Academic Unit
- Pathology
- Record Identifier
- 9984183986702771
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