Journal article
Medial Dorsal Thalamic Lesions Impair Blocking and Latent Inhibition of the Conditioned Eyeblink Response in Rats
Behavioral neuroscience, Vol.116(2), pp.276-285
04/2002
DOI: 10.1037/0735-7044.116.2.276
PMID: 11998820
Abstract
The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout training. The experiments in the present study tested the hypothesis that disruption of cingulothalamic stimulus processing produced by lesions of the MD would impair 2 types of associative learning that involve decremental changes in attention. In Experiment 1, MD lesions severely impaired blocking. In Experiment 2, MD lesions severely impaired LI. The results indicate that lesions of the MD impair incremental, decremental, or both types of changes in stimulus processing during learning.
Details
- Title: Subtitle
- Medial Dorsal Thalamic Lesions Impair Blocking and Latent Inhibition of the Conditioned Eyeblink Response in Rats
- Creators
- Daniel A Nicholson - Department of Psychology, University of IowaJohn H Freeman - Department of Psychology, University of Iowa
- Resource Type
- Journal article
- Publication Details
- Behavioral neuroscience, Vol.116(2), pp.276-285
- Publisher
- American Psychological Association
- DOI
- 10.1037/0735-7044.116.2.276
- PMID
- 11998820
- ISSN
- 0735-7044
- eISSN
- 1939-0084
- Language
- English
- Date published
- 04/2002
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984065755402771
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