Medial posterior meniscal root tears are associated with development or worsening of medial tibiofemoral cartilage damage: the multicenter osteoarthritis study

Ali Guermazi; Daichi Hayashi; Mohamed Jarraya; Frank W Roemer; Yuqing Zhang; Jingbo Niu; Michel D Crema; Martin Englund; John A Lynch; Michael C Nevitt; James C Torner; Cora E Lewis; David T Felson

doi:10.1148/radiol.13122544

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Medial posterior meniscal root tears are associated with development or worsening of medial tibiofemoral cartilage damage: the multicenter osteoarthritis study

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Medial posterior meniscal root tears are associated with development or worsening of medial tibiofemoral cartilage damage: the multicenter osteoarthritis study

Ali Guermazi, Daichi Hayashi, Mohamed Jarraya, Frank W Roemer, Yuqing Zhang, Jingbo Niu, Michel D Crema, Martin Englund, John A Lynch, Michael C Nevitt, …

Radiology, Vol.268(3), pp.814-821

09/2013

DOI: 10.1148/radiol.13122544

PMCID: PMC3750419

PMID: 23696679

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Abstract

To assess the association of meniscal root tear with the development or worsening of tibiofemoral cartilage damage. Institutional review board approval and written informed consent from all subjects were obtained. A total of 596 knees with radiographically depicted osteoarthritis were randomly selected from the Multicenter Osteoarthritis study cohort. Cartilage damage was semiquantitatively assessed by using the Whole-Organ Magnetic Resonance Imaging Score (WORMS) system (grades 0-6). Subjects were separated into three groups: root tear only, meniscal tear without root tear, and neither meniscal nor root tear. A log-binomial regression model was used to calculate the relative risks for knees to develop incident or progressing cartilage damage in the root tear group and the meniscal tear group, with the no tear group serving as a reference. In the medial tibiofemoral joint, there were 37 knees with isolated medial posterior root tear, 294 with meniscal tear without root tear, and 264 without meniscal or root tear. There were only two lateral posterior root tears, and no anterior root tears were found. Thus, the focus was on the medial posterior root tear. The frequency of severe cartilage damage (WORMS ≥ 5) was higher in the group with root tear than in the group without root or meniscal tear (76.7% vs 19.7%, P < .0001) but not in the group with meniscal but no root tear (76.7% vs 65.2%, P = .055). Longitudinal analyses included 33 knees with isolated medial posterior root tear, 270 with meniscal tear, and 245 with no tear. Adjusted relative risk of cartilage loss was 2.03 (95% confidence interval [CI]: 1.18, 3.48) for the root tear group and 1.84 (95% CI: 1.32, 2.58) for the meniscal tear group. Isolated medial posterior meniscal root tear is associated with incident and progressive medial tibiofemoral cartilage loss.

United States - epidemiology

Prevalence

Comorbidity

Humans

Middle Aged

Risk Factors

Fractures, Cartilage - pathology

Male

Osteoarthritis, Knee - epidemiology

Knee Injuries - epidemiology

Menisci, Tibial - pathology

Knee Injuries - pathology

Fractures, Cartilage - epidemiology

Osteoarthritis, Knee - pathology

Magnetic Resonance Imaging - statistics & numerical data

Female

Aged

Causality

Tibial Meniscus Injuries

Details

Title: Subtitle: Medial posterior meniscal root tears are associated with development or worsening of medial tibiofemoral cartilage damage: the multicenter osteoarthritis study
Creators: Ali Guermazi - Quantitative Imaging Center, Department of Radiology, and Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, 820 Harrison Ave, Boston, MA 02118, USA. guermazi@bu.edu
Daichi Hayashi
Mohamed Jarraya
Frank W Roemer
Yuqing Zhang
Jingbo Niu
Michel D Crema
Martin Englund
John A Lynch
Michael C Nevitt
James C Torner
Cora E Lewis
David T Felson
Resource Type: Journal article
Publication Details: Radiology, Vol.268(3), pp.814-821
DOI: 10.1148/radiol.13122544
PMID: 23696679
PMCID: PMC3750419
NLM abbreviation: Radiology
ISSN: 1527-1315
eISSN: 1527-1315
Publisher: United States
Grant note: U01 AG018947 / NIA NIH HHS U01 AG018832 / NIA NIH HHS AR47785 / NIAMS NIH HHS U01 AG019069 / NIA NIH HHS U01-AG-18820 / NIA NIH HHS P60 AR047785 / NIAMS NIH HHS U01-AG-18832 / NIA NIH HHS U01-AG-18947 / NIA NIH HHS U01-AG-19069 / NIA NIH HHS U01 AG018820 / NIA NIH HHS
Language: English
Date published: 09/2013
Academic Unit: Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
Record Identifier: 9983995060602771

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