Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features

K D Anand Rajan; Kiran Chikkanahalli Subbarao; Sandeep Agarwala; Siddhartha Datta Gupta

doi:10.4103/0377-4929.68297

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Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features

Journal article

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Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features

K D Anand Rajan, Kiran Chikkanahalli Subbarao, Sandeep Agarwala and Siddhartha Datta Gupta

Indian journal of pathology & microbiology, Vol.53(3), pp.525-534

07/2010

DOI: 10.4103/0377-4929.68297

PMID: 20699516

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Abstract

We hereby report the occurrence of mediastinal liposarcoma in a 11-year-old female child. Dyspnea and wheezing of long-standing duration were the presenting complaints and a preoperative biopsy failed to yield the diagnosis. Histologic examination revealed heterogeneous areas with well-differentiated liposarcoma-like areas, areas resembling myxoid liposarcoma, and areas of dedifferentiation. Osteosarcomatous foci and whorled areas reminiscent of meningioma were identified in the dedifferentiated areas. Liposarcomas in the mediastinum are extremely rare tumors of childhood and the present case showed unusual histologic features. Complete surgical excision with clear surgical margins remains the primary modality of treatment, although chemotherapy and radiotherapy have been tried.

Microscopy

Humans

Liposarcoma - pathology

Liposarcoma - diagnosis

Tomography, X-Ray Computed

Dyspnea - etiology

Mediastinal Neoplasms - diagnosis

Respiratory Sounds - etiology

Liposarcoma - surgery

Mediastinal Neoplasms - pathology

Histocytochemistry

Female

Radiography, Thoracic

Child

Mediastinal Neoplasms - surgery

Details

Title: Subtitle: Mediastinal liposarcoma of mixed type in childhood: a report of a case with unusual histologic features
Creators: K D Anand Rajan - Wilmer Eye Institute at the Johns Hopkins Hospital, Baltimore, MD 21287-9248, USA
Kiran Chikkanahalli Subbarao
Sandeep Agarwala
Siddhartha Datta Gupta
Resource Type: Journal article
Publication Details: Indian journal of pathology & microbiology, Vol.53(3), pp.525-534
DOI: 10.4103/0377-4929.68297
PMID: 20699516
NLM abbreviation: Indian J Pathol Microbiol
ISSN: 0377-4929
eISSN: 0974-5130
Publisher: India
Language: English
Date published: 07/2010
Academic Unit: Pathology
Record Identifier: 9984047666502771

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