Journal article
Medication Adherence and Persistence in Hypertension Management
Journal of clinical outcomes management, Vol.18(8), pp.351-358
08/01/2011
Abstract
To discuss barriers to adherence and persistence and present strategies for improving medication adherence and persistence in the management of hypertension. Review of the literature. Despite the use of antihypertensive medication, blood pressure remains uncontrolled in a substantial percentage (46%) of patients with hypertension. One important cause of refractory hypertension is medication-taking behavior (ie, poor adherence and persistence to medication regimens). Rates of nonadherence to antihypertensive medications range from 9% to 37%, while nonpersistence has been found to occur at even higher rates (30% to 50%) in patients 12 months after the initiation of antihypertensive therapy. Modifiable factors for these medication-taking behaviors include high pill burden, drug tolerability, and drug costs. Selection of medications that are better tolerated, such as angiotensinconverting enzyme inhibitors and angiotensin II receptor blockers, results in improved adherence and lower drug discontinuation rates compared to the use of the older, more poorly tolerated agents, diuretics and β blockers. Once-daily medications and fixed-dose combinations are strategies that can be considered to lessen the pill burden in patients with hypertension. Coordination of medication initiation in hypertensive patients with concomitant illness also increases adherence in these patients. Clinicians should consider and implement strategies that address the modifiable factors that contribute to low adherence and persistence with hypertension treatment.
Details
- Title: Subtitle
- Medication Adherence and Persistence in Hypertension Management
- Creators
- Jacqueline KlootwykCynthia Sanoski
- Resource Type
- Journal article
- Publication Details
- Journal of clinical outcomes management, Vol.18(8), pp.351-358
- Publisher
- Turner White Communications Inc
- ISSN
- 1079-6533
- eISSN
- 1938-1336
- Language
- English
- Date published
- 08/01/2011
- Academic Unit
- Pharmacy Practice and Science; Pharmacy
- Record Identifier
- 9984721126002771
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