Journal article
Memory performance in individuals with primary degenerative dementia: Its similarity to diazepam-induced impairments
Experimental aging research, Vol.11(3), pp.151-155
09/01/1985
DOI: 10.1080/03610738508259179
PMID: 4076305
Abstract
Impairments of memory storage and retrieval produced by diazepam (2.5 mg, 5 mg, and 10 mg) in normal elderly individuals were compared to those observed in patients with primary degenerative dementia tested under nondrug conditions. The highest diazepam dose affected retrieval as well as storage processes in Buschke's "selective reminding" task, producing impairments qualitatively similar to those shown by demented patients. All diazepam doses impaired Buschke task performance in the normal elderly individuals; normal young subjects, in contrast, showed no impairment with a low (2.5 mg) diazepam dose.
Details
- Title: Subtitle
- Memory performance in individuals with primary degenerative dementia: Its similarity to diazepam-induced impairments
- Creators
- Robert I Block - Department of Anesthesia , University of IowaMarlene Devoe - Department of Psychology , Wayne State University and Lafayette ClinicBarbara Stanley - Department of Psychiatry , Wayne State University and Lafayette ClinicMichael Stanley - Department of Pharmacology , Wayne State University and Lafayette ClinicNunzio Pomara - Department of Psychiatry , Wayne State University and Lafayette Clinic
- Resource Type
- Journal article
- Publication Details
- Experimental aging research, Vol.11(3), pp.151-155
- Publisher
- Taylor & Francis Group
- DOI
- 10.1080/03610738508259179
- PMID
- 4076305
- ISSN
- 0361-073X
- eISSN
- 1096-4657
- Language
- English
- Date published
- 09/01/1985
- Academic Unit
- Iowa Neuroscience Institute; Anesthesia
- Record Identifier
- 9984007161802771
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