Journal article
Mesalamine-Induced Myopericarditis: A Case Report and Literature Review
Cardiology research, Vol.10(1), pp.59-62
02/01/2019
DOI: 10.14740/cr820
PMCID: PMC6396800
PMID: 30834061
Abstract
Inflammation of the myocardium (myocarditis) or pericardium (pericarditis) or both (myopericarditis) as side effects of mesalamine, a drug widely used in the treatment of inflammatory bowel disease, is a rare, but potentially lethal complication. We report a case of myopericarditis occurring in a young Caucasian woman 14 days following initiation of mesalamine therapy for treatment of a newly diagnosed ulcerative colitis (UC). She presented with pleuritic chest pain, elevated troponin levels and pre-syncope. The diagnosis of myopericarditis was made based on the clinical features, electrocardiogram (EKG) and cardiac magnetic resonance, which showed trace pericardial effusion. The patient’s symptom and condition were dramatically improved upon discontinuing mesalamine, and a full recovery was achieved. Mesalamine-induced inflammation of the myocardium (myocarditis) or pericardium (pericarditis) or both (myopericarditis) is rare, but has fatal side effects. Early recognition of these side effects by clinicians and patients is important to prevent progression of the inflammation. Furthermore, patients should be educated to seek urgent medical attention if cardiac symptoms arise.
Details
- Title: Subtitle
- Mesalamine-Induced Myopericarditis: A Case Report and Literature Review
- Creators
- Mohamed E. Taha - University of Nevada, RenoAbubaker Abdalla - University of Nevada, RenoJaafar Al-Khafaji - University of Nevada, Reno School of MedicineSamira Malik - University of Nevada, Reno
- Resource Type
- Journal article
- Publication Details
- Cardiology research, Vol.10(1), pp.59-62
- DOI
- 10.14740/cr820
- PMID
- 30834061
- PMCID
- PMC6396800
- NLM abbreviation
- Cardiol Res
- ISSN
- 1923-2829
- eISSN
- 1923-2837
- Publisher
- Elmer Press
- Alternative title
- Mesalamine-Induced Myopericarditis
- Language
- English
- Date published
- 02/01/2019
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984695808002771
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