Journal article
Metabolic syndrome predicts incident disability and functional decline among Chinese older adults: results from the China Health and Retirement Longitudinal Study
Aging clinical and experimental research, Vol.33(11), pp.3073-3080
2021
DOI: 10.1007/s40520-021-01827-w
PMID: 33743170
Abstract
Aims
To investigate the longitudinal association of metabolic syndrome (MetS) and its components with disability outcomes.
Methods
A total of 5875 participants aged 60 and above completed the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study (CHARLS). MetS at baseline was measured by the National Cholesterol Education Program Adult Treatment Panel III criteria. Logistic regressions were conducted to analyze the associations between baseline MetS and incident disability, measured as the onset of limitations regarding instrumental activities of daily living (IADL) and activities of daily living (ADL) 4 years later. Linear regression was adopted to analyze the longitudinal impact of baseline MetS on the number of IADL and ADL limitations in 2015. A comprehensive list of baseline covariates was adjusted in all regression analyses.
Results
Baseline MetS was related to increased odds of incident IADL disability (OR = 1.28, 95% CI 1.05–1.55) and incident ADL disability (OR = 1.27, 95% CI 1.05–1.53) among disability-free participants at baseline. Baseline MetS was also associated with an increase in the number of IADL (beta = 0.15, 95% CI 0.07–0.23) and ADL limitations (beta = 0.10, 95% CI 0.01–0.18), while adjusting for baseline functional performance. Significant MetS component predictors of disability outcomes include abdominal obesity, high blood pressure, and a low level of high-density lipoprotein cholesterol.
Conclusions
Our findings suggest an increased risk of incident disability and deteriorated functional performance over 4 years, associated with the presence of MetS and its components.
Details
- Title: Subtitle
- Metabolic syndrome predicts incident disability and functional decline among Chinese older adults: results from the China Health and Retirement Longitudinal Study
- Creators
- Quan Zhang - Peking UniversityYi Wang - University of Iowa, School of Social WorkNan Yu - Ningxia Medical UniversityHua Ding - Institute of Social Science Survey, Peking UniversityDanyu Li - Central South UniversityXinyi Zhao - Peking University
- Resource Type
- Journal article
- Publication Details
- Aging clinical and experimental research, Vol.33(11), pp.3073-3080
- DOI
- 10.1007/s40520-021-01827-w
- PMID
- 33743170
- NLM abbreviation
- Aging Clin Exp Res
- ISSN
- 1594-0667
- eISSN
- 1720-8319
- Publisher
- Springer International Publishing
- Grant note
- 71704006 / National Natural Science Foundation of China (http://dx.doi.org/10.13039/501100001809) 16SRB006 / Beijing Social Science Fund (http://dx.doi.org/10.13039/501100009625)
- Language
- English
- Date published
- 2021
- Academic Unit
- School of Social Work
- Record Identifier
- 9984318050702771
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