Metabolism: Targeting a fat-accumulation gene

Charles Brenner

doi:10.1038/508194a

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Metabolism: Targeting a fat-accumulation gene

Journal article

Open access

Peer reviewed

Metabolism: Targeting a fat-accumulation gene

Charles Brenner

Nature, Vol.508(7495), pp.194-195

04/10/2014

DOI: 10.1038/508194a

PMID: 24717510

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https://doi.org/10.1038/508194aView

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Abstract

An enzyme that links two metabolic hubs has been found to be upregulated in the fat cells of overweight mice. Inhibition of the gene encoding this enzyme protects mice from diet-induced obesity.

Animals

Diet

Nicotinamide N-Methyltransferase - deficiency

Obesity - prevention & control

Male

Obesity - enzymology

Nicotinamide N-Methyltransferase - metabolism

Details

Title: Subtitle: Metabolism: Targeting a fat-accumulation gene
Creators: Charles Brenner - Department of Biochemistry, the Obesity Research Initiative, University of Iowa, Iowa City, Iowa 52242, USA
Resource Type: Journal article
Publication Details: Nature, Vol.508(7495), pp.194-195
DOI: 10.1038/508194a
PMID: 24717510
NLM abbreviation: Nature
ISSN: 0028-0836
eISSN: 1476-4687
Publisher: England
Language: English
Date published: 04/10/2014
Academic Unit: Biochemistry and Molecular Biology; Internal Medicine
Record Identifier: 9983788596402771

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