Metastatic Squamous Cell Carcinoma of the Tonsil Mimicking Choroidal Melanoma

Elaine M Binkley; Aron D Sampson; Nasreen A Syed; H Culver Boldt

doi:10.1159/000510288

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Metastatic Squamous Cell Carcinoma of the Tonsil Mimicking Choroidal Melanoma

Journal article

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Metastatic Squamous Cell Carcinoma of the Tonsil Mimicking Choroidal Melanoma

Elaine M Binkley, Aron D Sampson, Nasreen A Syed and H Culver Boldt

Ocular oncology and pathology, Vol.6(6), pp.405-409

12/2020

DOI: 10.1159/000510288

PMID: 33447590

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Abstract

We describe a case of a 53-year-old man with a history of metastatic squamous cell carcinoma of the tonsil who presented with a large, dome-shaped, choroidal mass in the left eye with concern for extra-ocular extension. Standardized echography showed a choroidal mass with low-to-medium internal reflectivity, pockets of very low reflectivity, positive angle kappa, and 1+ vascularity that were concerning for primary choroidal melanoma. Biopsy of the lesion was consistent with metastatic squamous cell carcinoma of the tonsil rather than melanoma. This is only the second reported case of metastatic squamous cell carcinoma to the choroid presenting with a large vascular tumor with echographic characteristics consistent with choroidal melanoma. The unique vascularity present in some cases of squamous cell carcinoma of the tonsil may explain the vascularity and large height of this patient's lesion. Tumor fine-needle aspiration biopsy can play an important role in patients with choroidal lesions in the setting of unusual primary tumors.

Squamous cell carcinoma

Melanoma

Choroidal metastasis

Details

Title: Subtitle: Metastatic Squamous Cell Carcinoma of the Tonsil Mimicking Choroidal Melanoma
Creators: Elaine M Binkley - Department of Ophthalmology and Visual Science, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Aron D Sampson - Department of Ophthalmology and Visual Science, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Nasreen A Syed - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
H Culver Boldt - Department of Ophthalmology and Visual Science, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Resource Type: Journal article
Publication Details: Ocular oncology and pathology, Vol.6(6), pp.405-409
DOI: 10.1159/000510288
PMID: 33447590
NLM abbreviation: Ocul Oncol Pathol
ISSN: 2296-4681
eISSN: 2296-4657
Language: English
Date published: 12/2020
Academic Unit: Pathology; Ophthalmology and Visual Sciences
Record Identifier: 9984172265002771

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