Journal article
Metastatic neuroblastoma with ganglioneuromatous differentiation and mandibular involvement
Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, Vol.88(5), pp.586-592
1999
DOI: 10.1016/S1079-2104(99)70090-9
PMID: 10556754
Abstract
Neuroblastic tumors comprise neuroblastoma (NB), ganglioneuroblastoma, and ganglioneuroma (GN). NBs have shown remarkable differentiation capabilities, which include spontaneous regression. In the last 3 decades, the prognosis for metastatic NB has improved significantly. The ability to distinguish prognostic subtypes based on clinical and biologic features allows for understanding of this disease process and development of management procedures. NBs are often asymptomatic and remain undetected until a large abdominal mass or metastasis is found. GN, the most differentiated variant, is a benign neoplasm with significant growth potential and ability to cause clinical complications. GN of the mandible has seldom been reported in the literature in English. We present a case of NB metastatic to the mandible exhibiting ganglioneuromatous differentiation. We discuss the current understanding of the biology, grading, classification, and prognostic implications of NB. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:586-92)
Details
- Title: Subtitle
- Metastatic neuroblastoma with ganglioneuromatous differentiation and mandibular involvement
- Creators
- Indraneel BhattacharyyaAnne WilliamsonDonald M CohenJohn L Bever
- Resource Type
- Journal article
- Publication Details
- Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, Vol.88(5), pp.586-592
- Publisher
- Mosby, Inc
- DOI
- 10.1016/S1079-2104(99)70090-9
- PMID
- 10556754
- ISSN
- 1079-2104
- eISSN
- 1528-395X
- Language
- English
- Date published
- 1999
- Academic Unit
- Endodontics
- Record Identifier
- 9984065706402771
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