Methamphetamine Use and Cardiovascular Disease In Search of Answers

Christopher G. Kevil; Nicholas E. Goeders; Matthew D. Woolard; Md Shenuarin Bhuiyan; Paari Dominic; Gopi K. Kolluru; Connie L. Arnold; James G. Traylor; A. Wayne Orr

doi:10.1161/ATVBAHA.119.312461

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Methamphetamine Use and Cardiovascular Disease In Search of Answers

Journal article

Open access

Peer reviewed

Methamphetamine Use and Cardiovascular Disease In Search of Answers

Christopher G. Kevil, Nicholas E. Goeders, Matthew D. Woolard, Md Shenuarin Bhuiyan, Paari Dominic, Gopi K. Kolluru, Connie L. Arnold, James G. Traylor and A. Wayne Orr

Arteriosclerosis, thrombosis, and vascular biology, Vol.39(9), pp.1739-1746

09/01/2019

DOI: 10.1161/ATVBAHA.119.312461

PMCID: PMC6709697

PMID: 31433698

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Abstract

While the opioid epidemic has garnered significant attention, the use of methamphetamines is growing worldwide independent of wealth or region. Following overdose and accidents, the leading cause of death in methamphetamine users is cardiovascular disease, because of significant effects of methamphetamine on vasoconstriction, pulmonary hypertension, atherosclerotic plaque formation, cardiac arrhythmias, and cardiomyopathy. In this review, we examine the current literature on methamphetamine-induced changes in cardiovascular health, discuss the potential mechanisms regulating these varied effects, and highlight our deficiencies in understanding how to treat methamphetamine-associated cardiovascular dysfunction.

Cardiovascular System & Cardiology

Hematology

Life Sciences & Biomedicine

Peripheral Vascular Disease

Science & Technology

Details

Title: Subtitle: Methamphetamine Use and Cardiovascular Disease In Search of Answers
Creators: Christopher G. Kevil - Louisiana State University Health Sciences Center Shreveport
Nicholas E. Goeders - Louisiana State University Health Sciences Center Shreveport
Matthew D. Woolard - Louisiana State University Health Sciences Center Shreveport
Md Shenuarin Bhuiyan - Louisiana State University Health Sciences Center Shreveport
Paari Dominic - Louisiana State University Health Sciences Center Shreveport
Gopi K. Kolluru - Louisiana State University Health Sciences Center Shreveport
Connie L. Arnold - Louisiana State University Health Sciences Center Shreveport
James G. Traylor - Louisiana State University Health Sciences Center Shreveport
A. Wayne Orr - Louisiana State University Health Sciences Center Shreveport
Resource Type: Journal article
Publication Details: Arteriosclerosis, thrombosis, and vascular biology, Vol.39(9), pp.1739-1746
DOI: 10.1161/ATVBAHA.119.312461
PMID: 31433698
PMCID: PMC6709697
NLM abbreviation: Arterioscler Thromb Vasc Biol
ISSN: 1079-5642
eISSN: 1524-4636
Publisher: Lippincott Williams & Wilkins
Number of pages: 8
Grant note: R01 HL098435; HL133497; HL141155; HL131844; HL122354; HL145753 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R01HL131844 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) P20GM121307 / NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of General Medical Sciences (NIGMS) P20GM121307 / Institutional Development Award from the National Institutes of General Medical Sciences of the National Institutes of Health (NIH)
Language: English
Date published: 09/01/2019
Academic Unit: Internal Medicine
Record Identifier: 9984367134802771

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