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Methemoglobinemia: an unusual cause of postoperative cyanosis
Journal article   Open access   Peer reviewed

Methemoglobinemia: an unusual cause of postoperative cyanosis

Carryn M Anderson, Kenneth J Woodside, Todd A Spencer and Glenn C Hunter
Journal of vascular surgery, Vol.39(3), pp.686-690
03/2004
DOI: 10.1016/j.jvs.2003.08.023
PMID: 14981472
url
https://doi.org/10.1016/j.jvs.2003.08.023View
Published (Version of record) Open Access

Abstract

Methemoglobinemia, although rare, must be considered in surgical patients presenting with acute respiratory distress and cyanosis. We report two cases of methemoglobinemia in patients undergoing aortic reconstruction. The first patient developed methemoglobinemia while on a nitroglycerin infusion, and the second after receiving benzocaine spray before intubation. Both patients were treated with methylene blue and ascorbic acid, with resolution of their hypoxia and cyanosis. The pathophysiology, etiology, diagnosis, and treatment of methemoglobinemia are reviewed.
Humans Middle Aged Methemoglobinemia - diagnosis Methemoglobinemia - physiopathology Cyanosis - therapy Treatment Outcome Methemoglobinemia - etiology Enzyme Inhibitors - therapeutic use Antioxidants - therapeutic use Ascorbic Acid - therapeutic use Methylene Blue - therapeutic use Female Aged Methemoglobinemia - therapy Cyanosis - etiology Postoperative Complications Blood Vessel Prosthesis Implantation

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