Journal article
Methods Used to Study Immunoregulation of Schistosome Egg Granulomas
Methods (San Diego, Calif.), Vol.9(2), pp.255-267
04/1996
DOI: 10.1006/meth.1996.0032
PMID: 8812679
Abstract
The schistosome egg granuloma has emerged as a dominant model system to study the immunoregulation of focal inflammatory reactions. The pervasive Th2 character of schistosome egg granulomas has further increased interest in this parasite infection. This review will discuss the common methods used to study schistosome egg granulomas. This includes the choice of parasite, maintenance of parasite life cycle, animal infection, granuloma isolation, and analysis of granuloma cells. The review includes a survey of recent observations and conclusions concerning the immunoregulation of granulomatous reactions. Emphasis is placed on the cytokines and cell types that participate in forming schistosome egg granulomas. The pitfalls, assumptions, and limits of various experimental approaches are described.
Details
- Title: Subtitle
- Methods Used to Study Immunoregulation of Schistosome Egg Granulomas
- Creators
- David E Elliott - Department of Internal Medicine, University of Iowa Hospitals and Clinics, University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Methods (San Diego, Calif.), Vol.9(2), pp.255-267
- Publisher
- Elsevier Inc
- DOI
- 10.1006/meth.1996.0032
- PMID
- 8812679
- ISSN
- 1046-2023
- eISSN
- 1095-9130
- Language
- English
- Date published
- 04/1996
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094748502771
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