Journal article
Methods for fabricating oxygen releasing biomaterials
Journal of drug targeting, Vol.30(2), pp.188-199
02/07/2022
DOI: 10.1080/1061186X.2021.1971235
PMID: 34486908
Abstract
Sustained external supply of oxygen (O
2
) to engineered tissue constructs is important for their survival in the body while angiogenesis is taking place. In the recent years, the trend towards the fabrication of various O
2
-generating materials that can provide prolonged and controlled O
2
source to the large volume tissue constructs resulted in preventing necrosis associated with the lack of O
2
supply. In this review, we explain different methods employed in the fabrication of O
2
-generating materials such as emulsion, microfluidics, solvent casting, freeze drying, electrospraying, gelation, microfluidic and three-dimensional (3D) bioprinting methods. After discussing pros and cons of each method, we review physical, chemical, and biological characterisation techniques used to analyse the resulting product. Finally, the challenges and future directions in the field are discussed.
Details
- Title: Subtitle
- Methods for fabricating oxygen releasing biomaterials
- Creators
- Ahmet Erdem - Kocaeli ÜniversitesiReihaneh Haghniaz - University of California, Los AngelesYavuz Nuri Ertas - Erciyes UniversitySiva Koti Sangabathuni - University of California, Los AngelesAli S. Nasr - University of IowaWojciech Swieszkowski - Warsaw University of TechnologyNureddin Ashammakhi - University of California, Los Angeles
- Resource Type
- Journal article
- Publication Details
- Journal of drug targeting, Vol.30(2), pp.188-199
- Publisher
- Taylor & Francis
- DOI
- 10.1080/1061186X.2021.1971235
- PMID
- 34486908
- ISSN
- 1061-186X
- eISSN
- 1029-2330
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health, award: 1UG3TR003148-01; DOI: 10.13039/100000968, name: American Heart Association, award: 18TPA34230036, 442611-NU80922
- Language
- English
- Date published
- 02/07/2022
- Academic Unit
- Surgery
- Record Identifier
- 9984322947402771
Metrics
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