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Microbial susceptibility to calcium hydroxide pastes and their vehicles
Journal article   Peer reviewed

Microbial susceptibility to calcium hydroxide pastes and their vehicles

Brenda Paula Figueiredo de Almeida Gomes, Fabricio Batista Teixeira, Caio Cezar Randi Ferraz, Fabio Devora Garrido, Pedro Luiz Rosalen, Alexandre Augusto Zaia and Francisco José de Souza-Filho
Journal of endodontics, Vol.28(11), pp.758-761
11/2002
DOI: 10.1097/00004770-200211000-00003
PMID: 12470019

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Abstract

The aim of this study was to investigate the susceptibility of some microorganisms commonly isolated from root canals to calcium hydroxide in combination with several vehicles by the agar diffusion method. Stainless-steel cylinders were placed on each inoculated agar medium. The test medications and their controls were placed inside the cylinders. The zones of growth inhibition were measured and recorded after the incubation period for each plate, and the results were analyzed statistically. Enterococcus faecalis was most resistant, whereas the anaerobic Porphyromonas endodontalis was more susceptible to all medications, followed by P. gingivalis and Prevotella intermedial intermedia. Ca(OH)2 + CMCP + glycerin showed significantly larger mean zones of inhibition when compared with the other medications. We conclude that anaerobic Gram-negative bacteria are more susceptible to calcium hydroxide pastes than facultative Gram-positive microorganisms.
Calcium Hydroxide - pharmacology Enterococcus faecalis - drug effects Porphyromonas - drug effects Prevotella intermedia - drug effects Humans Drug Resistance, Bacterial Colony Count, Microbial Dental Pulp Cavity - microbiology Streptococcus - drug effects Culture Media Glycerol - pharmacology Bacteria, Anaerobic - drug effects Camphor - pharmacology Gram-Negative Anaerobic Bacteria - drug effects Ointments Polyethylene Glycols - pharmacology Excipients Actinomyces - drug effects Agar Prevotella - drug effects Chlorophenols - pharmacology Analysis of Variance Root Canal Filling Materials - pharmacology Drug Combinations Pharmaceutical Vehicles Porphyromonas gingivalis - drug effects

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