Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population

Salim Dogru; Eric P Wilkinson; Robert A Robinson; Richard J.H Smith

doi:10.1016/j.ijporl.2009.02.014

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Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population

Journal article

Peer reviewed

Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population

Salim Dogru, Eric P Wilkinson, Robert A Robinson and Richard J.H Smith

International journal of pediatric otorhinolaryngology, Vol.73(6), pp.895-898

2009

DOI: 10.1016/j.ijporl.2009.02.014

PMID: 19303146

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Abstract

Middle ear adenoma with neuroendocrine differentiation is an uncommon tumor of the tympanic cavity. The terminology of this entity has suffered due to a poor understanding of the differentiation of these neoplasms, and has included both “adenoma” as well as “carcinoid tumor.” Immunohistochemical techniques have helped clarify that these tumors all share elements of neuroendocrine differentiation. Occurrences of this tumor in the pediatric population are extremely rare. In the world literature, only three pediatric cases of middle ear adenoma with neuroendocrine differentiation have been described. We report the youngest case to date of middle ear adenoma with neuroendocrine differentiation, in a 13-year-old boy. We discuss the differential diagnosis, surgical management, and pathology of this entity.

Adenoma

Middle ear

Carcinoid tumor

Neuroendocrine tumor

Details

Title: Subtitle: Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population
Creators: Salim Dogru - Department of Otolaryngology, Haydarpasa Training Hospital, Kadikoy, Istanbul, 34668, Turkey
Eric P Wilkinson - House Clinic, Los Angeles, CA, United States
Robert A Robinson - Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, United States
Richard J.H Smith - Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, United States
Resource Type: Journal article
Publication Details: International journal of pediatric otorhinolaryngology, Vol.73(6), pp.895-898
DOI: 10.1016/j.ijporl.2009.02.014
PMID: 19303146
NLM abbreviation: Int J Pediatr Otorhinolaryngol
ISSN: 0165-5876
eISSN: 1872-8464
Publisher: Elsevier Ireland Ltd
Language: English
Date published: 2009
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Oral Pathology, Radiology and Medicine; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Pathology; Iowa Neuroscience Institute; Otolaryngology; Internal Medicine
Record Identifier: 9984006454902771

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