Minimally Invasive Glaucoma Surgery: Latest Developments and Future Challenges

Poemen P. M. Chan; Mark D. Larson; Jaime E. Dickerson; Karl Mercieca; Victor Teck Chang Koh; Ridia Lim; Enne Hiu Ying Leung; Thomas W. Samuelson; Christine L. Larsen; Alison Harvey; Marc Toeteberg-Harms; Frances Meier-Gibbons; Nicole Shu-Wen Chan; Jessica Belle Sy; Kaweh Mansouri; Xiulan Zhang; Dennis S. C. Lam

doi:10.1097/APO.0000000000000646

Back

Minimally Invasive Glaucoma Surgery: Latest Developments and Future Challenges

Journal article

Open access

Peer reviewed

Minimally Invasive Glaucoma Surgery: Latest Developments and Future Challenges

Poemen P. M. Chan, Mark D. Larson, Jaime E. Dickerson, Karl Mercieca, Victor Teck Chang Koh, Ridia Lim, Enne Hiu Ying Leung, Thomas W. Samuelson, Christine L. Larsen, Alison Harvey, …

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), Vol.12(6), pp.537-564

11/01/2023

DOI: 10.1097/APO.0000000000000646

PMID: 38079242

Files and links (1)

url

https://doi.org/10.1097/APO.0000000000000646View

Published (Version of record) Open Access

Abstract

The development of minimally invasive glaucoma surgeries (MIGSs) was intended to provide safe and modestly efficacious modalities for early intervention of mild-to-moderate glaucoma, with minimal trauma and rapid recovery. They were mainly ab interno procedures that reduce intraocular pressure by facilitating the aqueous outflow by bypassing the trabecular meshwork resistance, reinforcing the uveoscleral flow via the supraciliary space, and reducing aqueous production by the ciliary body. While the cumulating evidence helps shape the role of the available MIGS, the exponential new development and advancement in this field has expanded the territory of MIGS. Apart from developing subconjunctival MIGS filtration devices (Xen gel stent and PRESERFLO MicroShunt), there is a tendency to revisit the "traditional" MIGS for alternative use and to modify the procedures with consideration of the fundamental aqueous outflow physiology. Combined MIGS has also been suggested, based on the theory that their different mechanisms may provide additive or synergistic effects. The advancement of laser procedures is also promising and could supplement unmet needs along the glaucoma treatment algorithm. This review examines the broad array of MIGS, updates the recent findings, discusses their potential alternative applications, and explores future challenges.

Life Sciences & Biomedicine

Ophthalmology

Science & Technology

Details

Title: Subtitle: Minimally Invasive Glaucoma Surgery: Latest Developments and Future Challenges
Creators: Poemen P. M. Chan - Chinese University of Hong Kong
Mark D. Larson - Minnesota Eye Consultants
Jaime E. Dickerson - Menlo School
Karl Mercieca - Univ Hosp Eye Clin, Bonn, Germany
Victor Teck Chang Koh - Natl Univ Hlth Syst, Dept Ophthalmol, Singapore, Singapore
Ridia Lim - Sydney Hospital
Enne Hiu Ying Leung - C MER Dennis Lam & Partners Eye Ctr, C MER Int Eye Care Grp, Hong Kong, Peoples R China
Thomas W. Samuelson - Minnesota Eye Consultants
Christine L. Larsen - Minnesota Eye Consultants
Alison Harvey - Menlo School
Marc Toeteberg-Harms - Augusta University
Frances Meier-Gibbons - University of Applied Sciences Rapperswil
Nicole Shu-Wen Chan - Natl Univ Hlth Syst, Dept Ophthalmol, Singapore, Singapore
Jessica Belle Sy - Sydney Hospital
Kaweh Mansouri - Clinique Valmont
Xiulan Zhang - Sun Yat-sen University
Dennis S. C. Lam - Chinese University of Hong Kong, Shenzhen
Resource Type: Journal article
Publication Details: Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), Vol.12(6), pp.537-564
DOI: 10.1097/APO.0000000000000646
PMID: 38079242
NLM abbreviation: Asia Pac J Ophthalmol (Phila)
ISSN: 2162-0989
eISSN: 2162-0989
Publisher: Asia-Pacific Acad Ophthalmology-Apao
Number of pages: 28
Language: English
Date published: 11/01/2023
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9984696720602771

Metrics

56 Record Views

35 Times Cited - Web of Science