Journal article
Minocycline-induced lupus
Drug and therapeutics bulletin, Vol.64(2), pp.28-31
02/2026
DOI: 10.1136/dtb.2025.262755rep
PMID: 40721232
Abstract
Summary
Antibiotics are indicated for inappropriately prolonged durations not only for infectious diseases but also for non-infectious dermatologic conditions such as acne vulgaris, but inappropriate use is not uncommon. Inappropriate antibiotic prescription can contribute to the emergence of multidrug-resistant organisms, patient harm such as adverse drug events and increased healthcare costs. We experienced a case involving a late adolescent with acne vulgaris who had been treated with minocycline for more than 2 years, leading to the development of drug-induced lupus, attributed to minocycline. This resulted in multiple clinic and emergency department visits and extensive and expensive workups, including an invasive procedure. A collaboration between antibiotic stewardship activities and patient-centred medication reviews, followed by personalised deprescribing, could effectively mitigate inappropriate antibiotic prescriptions for non-infectious dermatologic conditions.
Details
- Title: Subtitle
- Minocycline-induced lupus
- Creators
- Shinya Hasegawa - University of IowaSteven M Craig - Rheumatology, Iowa Arthritis and Osteoporosis Center, Urbandale, Iowa, USAHiroyuki Suzuki - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Drug and therapeutics bulletin, Vol.64(2), pp.28-31
- DOI
- 10.1136/dtb.2025.262755rep
- PMID
- 40721232
- NLM abbreviation
- Drug Ther Bull
- ISSN
- 0012-6543
- eISSN
- 1755-5248
- Publisher
- BMJ Publishing Group Ltd
- Language
- English
- Electronic publication date
- 07/27/2025
- Date published
- 02/2026
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9984927086602771
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