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Mitochondrial Encephalopathy and Optic Neuropathy Due to m.10158 MT-ND3 Complex I Mutation Presenting in an Adult Patient: Case Report and Review of the Literature
Journal article   Peer reviewed

Mitochondrial Encephalopathy and Optic Neuropathy Due to m.10158 MT-ND3 Complex I Mutation Presenting in an Adult Patient: Case Report and Review of the Literature

Ivana Vodopivec, Tracey A Cho, Joseph F Rizzo III, Matthew P Frosch and Katherine B Sims
The Neurologist (Baltimore, Md.), Vol.21(4), pp.61-65
07/2016
DOI: 10.1097/NRL.0000000000000084
PMID: 27348141

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Abstract

Establishing a diagnosis of mitochondrial disease in adults remains a clinician's challenge. We report a case of syndrome reminiscent of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) in an adult patient who carries m.10158T>C mutation in complex I respiratory chain gene MT-ND3 (mitochondrially encoded NADH dehydrogenase 3).
MELAS Syndrome - genetics MELAS Syndrome - diagnosis Electron Transport Complex I - genetics Humans Optic Nerve Diseases - diagnosis Adult Male Mutation - genetics Optic Nerve Diseases - genetics

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