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Published (Version of record)CC BY-NC V4.0, Open Access
Journal article
Modeling planar response of vascular tissues using quadratic functions of effective strain
International journal for numerical methods in biomedical engineering, Vol.39(4), e3653
04/2023
DOI: 10.1002/cnm.3653
Appears in UI Libraries Support Open Access
Abstract
Simulation-based studies of the cardiovascular structure such as aorta have become increasingly popular for many biomedical problems such as predictions of aneurysm rupture. A critical step in these simulations is the development of constitutive models that accurately describe the tissue's mechanical behavior. In this work, we present a new constitutive model, which explicitly accounts for the gradual recruitment of collagen fibers. The recruitment is considered using an effective stretch, which is a continuum-scale kinematic variable measuring the uncrimped stretch of the tissue in an average sense. The strain energy of a fiber bundle is described by a quadratic function of the effective strain. Constitutive models formulated in this manner are applied to describe the responses of ascending thoracic aortic aneurysm and porcine thoracic aorta tissues. The heterogeneous properties of the ATAA tissue are extracted from bulge inflation test data, and then used in finite element analysis to simulate the inflation test. The descriptive and predictive capabilities are further assessed using planar testing data of porcine thoracic aortic tissues. It is found that the constitutive model can accurately describe the stress–strain relations. In particular, the finite element simulation replicates the displacement, strain, and stress distributions with excellent fidelity.
Details
- Title: Subtitle
- Modeling planar response of vascular tissues using quadratic functions of effective strain
- Creators
- Xuehuan He - University of IowaJia Lu - University of Iowa
- Resource Type
- Journal article
- Publication Details
- International journal for numerical methods in biomedical engineering, Vol.39(4), e3653
- Publisher
- Wiley
- DOI
- 10.1002/cnm.3653
- eISSN
- 2040-7947
- Language
- English
- Electronic publication date
- 09/27/2022
- Date published
- 04/2023
- Academic Unit
- Mechanical Engineering
- Record Identifier
- 9984302597402771
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