Journal article
Modeling protein–DNA complexes with tangles
Computers & mathematics with applications (1987), Vol.55(5), pp.924-937
2008
DOI: 10.1016/j.camwa.2006.12.099
Abstract
The mathematics of tangles has been applied to model protein–DNA binding. A tangle consists of strings properly embedded in a 3-dimensional ball. The protein complex can be thought of as a 3D ball while the DNA segments bound by the protein complex can be thought of as strings embedded within the ball. This simple model can be used to determine the topology of protein-bound DNA. We review some tangle models and related software for modeling recombinase and topoisomerase action.
Details
- Title: Subtitle
- Modeling protein–DNA complexes with tangles
- Creators
- Isabel K Darcy - Mathematics Department, University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Computers & mathematics with applications (1987), Vol.55(5), pp.924-937
- DOI
- 10.1016/j.camwa.2006.12.099
- ISSN
- 0898-1221
- eISSN
- 1873-7668
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 2008
- Academic Unit
- Mathematics
- Record Identifier
- 9983985942902771
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