Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders

K E Markon

doi:10.1017/S0033291709990183

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Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders

Journal article

Peer reviewed

Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders

K E Markon

Psychological medicine, Vol.40(2), pp.273-288

02/2010

DOI: 10.1017/S0033291709990183

PMID: 19515267

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Abstract

Analyses of co-morbidity patterns among common mental disorders have repeatedly indicated that relationships among disorders can be understood in terms of broad superordinate dimensions. However, these analyses have been based on syndromal-level indicators, which are often heterogeneous, rather than on symptoms, which are presumably more homogeneous. Symptom-level exploratory and confirmatory analyses were used to explore the joint hierarchical organization of Axis I and II psychopathology, using data on 8405 individuals from the 2000 British Psychiatric Morbidity Survey. Analyses indicated that 20 identified subordinate dimensions of psychopathology could be organized into four broad superordinate dimensions: Internalizing, Externalizing, Thought Disorder, and Pathological Introversion. These results extend existing model frameworks 'downward' as well as 'outward', by analyzing symptoms rather than diagnoses, and by integrating symptoms from Axis I and II disorders in a common framework. This model demonstrates the importance of hierarchy in psychopathology structure, comprises replicable features of psychopathology structure, and has important implications for understanding the nature and organization of mental disorders.

Severity of Illness Index

Diagnostic and Statistical Manual of Mental Disorders

Mental Disorders - epidemiology

Prevalence

Comorbidity

Humans

Middle Aged

Risk Factors

Thinking

Models, Psychological

Social Desirability

Male

Mental Disorders - psychology

Young Adult

Adolescent

Adult

Female

Surveys and Questionnaires

Aged

Personality Disorders - psychology

Mental Disorders - diagnosis

Personality Disorders - diagnosis

Personality Disorders - epidemiology

Details

Title: Subtitle: Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders
Creators: K E Markon - Department of Psychology, University of Iowa, Iowa City, IA 52242, USA. kristian-markon@uiowa.edu
Resource Type: Journal article
Publication Details: Psychological medicine, Vol.40(2), pp.273-288
DOI: 10.1017/S0033291709990183
PMID: 19515267
ISSN: 0033-2917
eISSN: 1469-8978
Language: English
Date published: 02/2010
Academic Unit: Psychological and Brain Sciences
Record Identifier: 9984083271202771

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