Journal article
Modulation of response patterns in human auditory cortex during a target detection task: An intracranial electrophysiology study
International journal of psychophysiology, Vol.95(2), pp.191-201
02/2015
DOI: 10.1016/j.ijpsycho.2014.03.006
PMCID: PMC4430839
PMID: 24681353
Abstract
Selective attention enhances cortical activity representing an attended sound stream in human posterolateral superior temporal gyrus (PLST). It is unclear, however, what mechanisms are associated with a target detection task that necessitates sustained attention (vigilance) to a sound stream. We compared responses elicited by target and non-target sounds, and to sounds presented in a passive-listening paradigm. Subjects were neurosurgical patients undergoing invasive monitoring for medically refractory epilepsy. Stimuli were complex tones, band-limited noise bursts and speech syllables. High gamma cortical activity (70–150Hz) was examined in all subjects using subdural grid electrodes implanted over PLST. Additionally, responses were measured from depth electrodes implanted within Heschl's gyrus (HG) in one subject. Responses to target sounds recorded from PLST were increased when compared to responses elicited by the same sounds when they were not-targets, and when they were presented during passive listening. Increases in high gamma activity to target sounds occurred during later portions (after 250ms) of the response. These increases were related to the task and not to detailed stimulus characteristics. In contrast, earlier activity that did not vary across conditions did represent stimulus acoustic characteristics. Effects observed on PLST were not noted in HG. No consistent effects were noted in the averaged evoked potentials in either cortical region. We conclude that task dependence modulates later activity in PLST during vigilance. Later activity may represent feedback from higher cortical areas. Study of concurrently recorded activity from frontoparietal areas is necessary to further clarify task-related modulation of activity on PLST.
•Target-detection tasks increase high gamma activity in human auditory cortex.•Modulation primarily occurs on posterolateral superior temporal gyrus.•Target-specific activity occurs during later portions of the response.•Activity representing acoustic features occurs early in the response.•There is no consistent modulation of evoked potentials.
Details
- Title: Subtitle
- Modulation of response patterns in human auditory cortex during a target detection task: An intracranial electrophysiology study
- Creators
- Kirill V Nourski - Department of Neurosurgery, The University of Iowa, Iowa City, IA 52242, USAMitchell Steinschneider - Department of Neurology, Albert Einstein College of Medicine, New York, NY 10461, USAHiroyuki Oya - Department of Neurosurgery, The University of Iowa, Iowa City, IA 52242, USAHiroto Kawasaki - Department of Neurosurgery, The University of Iowa, Iowa City, IA 52242, USAMatthew A Howard - Department of Neurosurgery, The University of Iowa, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- International journal of psychophysiology, Vol.95(2), pp.191-201
- DOI
- 10.1016/j.ijpsycho.2014.03.006
- PMID
- 24681353
- PMCID
- PMC4430839
- NLM abbreviation
- Int J Psychophysiol
- ISSN
- 0167-8760
- eISSN
- 1872-7697
- Publisher
- Elsevier B.V
- Grant note
- DOI: 10.13039/100000002, name: NIH, award: R01-DC04290, R01-DC00657, UL1RR024979; DOI: 10.13039/100002046, name: Hearing Health Foundation; name: Hoover Fund
- Language
- English
- Date published
- 02/2015
- Academic Unit
- Neurology; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040254802771
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