Journal article
Molecular Detection of Micrometastatic Breast Cancer in Histopathology-Negative Axillary Lymph Nodes Correlates With Traditional Predictors of Prognosis: An Interim Analysis of a Prospective Multi-Institutional Cohort Study
Annals of surgery, Vol.239(6), pp.828-840
06/2004
DOI: 10.1097/01.sla.0000128687.59439.d6
PMCID: PMC1356291
PMID: 15166962
Abstract
The association between real-time RT-PCR results and traditional predictors of prognosis provide strong evidence that molecular markers serve as valid surrogates for the detection of micrometastatic breast cancer.
Details
- Title: Subtitle
- Molecular Detection of Micrometastatic Breast Cancer in Histopathology-Negative Axillary Lymph Nodes Correlates With Traditional Predictors of Prognosis: An Interim Analysis of a Prospective Multi-Institutional Cohort Study
- Creators
- William E Gillanders - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCKaidi Mikhitarian - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCRenee Hebert - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCPatrick D Mauldin - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCYuko Palesch - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCChristian Walters - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCMarshall M Urist - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCG Bruce Mann - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCGerard Doherty - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCVirginia M Herrmann - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCArnold D Hill - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCOleg Eremin - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCMohamed El-Sheemy - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCRichard K Orr - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCAlvaro A Valle - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCMichael A Henderson - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCRobert L Dewitty - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCSonia L Sugg - University of Iowa, SurgeryEric Frykberg - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCKaren Yeh - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCRichard M Bell - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCJohn S Metcalf - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCBruce M Elliott - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCThomas Brothers - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCJay Robison - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCMichael Mitas - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SCDavid J Cole - From the Department of Surgery, Medical University of South Carolina, Charleston, SC; †The Clinical Innovation Group, Charleston, SC; ‡Department of Pharmacy Practice, Medical University of South Carolina, Charleston, SC; §Department of Biometry & Epidemiology, Medical University of South Carolina, Charleston, SC; ¶Department of Surgery, University of Alabama, Birmingham, AL; ∥Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria, Australia; Department of Surgery, University of Michigan, Ann Arbor, MI;††Department of Surgery, Washington University, St. Louis, MO; ‡‡Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland; §§Department of Surgery, Lincoln & Louth County Hospital, Lincoln, England; ¶¶Department of Surgery, Spartanburg Regional Medical Center, Spartanburg, SC; ∥∥Department of Surgery, University of Tennessee, Chattanooga, TN; Department of Surgery, St. Vincent's Hospital,Victoria, Australia; †††Howard University Cancer Center, Washington, DC; ‡‡‡Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; §§§Department of Surgery, University of Florida Hospital, Jacksonville, FL; ¶¶¶Department of Surgery, Medical College of Georgia, Augusta, GA; ∥∥∥Department of Surgery, Palmetto Health Alliance, Columbia, SC; and Department of Pathology, Medical University of South Carolina, Charleston, SC
- Resource Type
- Journal article
- Publication Details
- Annals of surgery, Vol.239(6), pp.828-840
- DOI
- 10.1097/01.sla.0000128687.59439.d6
- PMID
- 15166962
- PMCID
- PMC1356291
- NLM abbreviation
- Ann Surg
- ISSN
- 0003-4932
- eISSN
- 1528-1140
- Language
- English
- Date published
- 06/2004
- Academic Unit
- Surgery
- Record Identifier
- 9984051742102771
Metrics
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