Molecular Epidemiology of Large COVID-19 Clusters before and after the Implementation of Routine Serial Testing at an Academic Medical Center — Iowa, 2020

Miguel E. Ortiz; Takaaki Kobayashi; Katherine Imborek; Mohammed Alsuhaibani; Stephanie Holley; Alexandra Trannel; Alexandre R. Marra; William Etienne; Kyle E. Jenn; Oluchi J. Abosi; Holly Meacham; Lorinda Sheeler; Angelique Dains; Mary E. Kukla; Paul B. McCray; Stanley Perlman; Bradley Ford; Daniel J. Diekema; Melanie Wellington; Alejandro A. Pezzulo; Jorge L. Salinas

doi:10.1017/ice.2021.301

Back

Molecular Epidemiology of Large COVID-19 Clusters before and after the Implementation of Routine Serial Testing at an Academic Medical Center — Iowa, 2020

Journal article

Open access

Peer reviewed

Molecular Epidemiology of Large COVID-19 Clusters before and after the Implementation of Routine Serial Testing at an Academic Medical Center — Iowa, 2020

Miguel E. Ortiz, Takaaki Kobayashi, Katherine Imborek, Mohammed Alsuhaibani, Stephanie Holley, Alexandra Trannel, Alexandre R. Marra, William Etienne, Kyle E. Jenn, Oluchi J. Abosi, …

Infection Control & Hospital Epidemiology, Vol.42(12), pp.1514-1516

06/24/2021

DOI: 10.1017/ice.2021.301

PMCID: PMC8267241

PMID: 34229775

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267241View

Published (Version of record) Open Access

Abstract

Coronavirus disease 2019 (COVID-19) is a multisystemic illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Preventing SARS-CoV-2 transmission in healthcare settings is challenging. Several strategies for early identification and isolation have been implemented, including SARS-CoV-2 screening of patients on admission. 1 However, because SARS-CoV-2 has a median incubation period of ~5 days, infected patients may have negative results at the time of admission. Undetected cases during hospital admission may contribute to nosocomial transmission and outbreaks. 2,3 Investigating hospital COVID-19 outbreaks is challenging because of the multitude of patient interactions and the high incidence in the community. Viral genome sequencing data can help discern healthcare-associated from community-associated infections. We describe 2 large COVID-19 clusters identified in our hospital before and after the implementation of serial testing. We applied molecular epidemiology to confirm nosocomial transmission.

Details

Title: Subtitle: Molecular Epidemiology of Large COVID-19 Clusters before and after the Implementation of Routine Serial Testing at an Academic Medical Center — Iowa, 2020
Creators: Miguel E. Ortiz
Takaaki Kobayashi
Katherine Imborek
Mohammed Alsuhaibani
Stephanie Holley
Alexandra Trannel
Alexandre R. Marra
William Etienne
Kyle E. Jenn
Oluchi J. Abosi
Holly Meacham
Lorinda Sheeler
Angelique Dains
Mary E. Kukla
Paul B. McCray
Stanley Perlman
Bradley Ford
Daniel J. Diekema
Melanie Wellington
Alejandro A. Pezzulo
Jorge L. Salinas
Resource Type: Journal article
Publication Details: Infection Control & Hospital Epidemiology, Vol.42(12), pp.1514-1516
Publisher: Cambridge University Press
DOI: 10.1017/ice.2021.301
PMID: 34229775
PMCID: PMC8267241
ISSN: 0899-823X
eISSN: 1559-6834
Language: English
Date published: 06/24/2021
Academic Unit: Microbiology and Immunology; Pulmonary Medicine; Infectious Diseases; Stead Family Department of Pediatrics; Pathology; Iowa Neuroscience Institute; Family and Community Medicine; Infectious Disease (Pediatrics); Internal Medicine
Record Identifier: 9984093784302771

Metrics

25 Record Views

3 Times Cited - Web of Science

See more details