Journal article
Molecular Targeted alpha-Particle Therapy for Oncologic Applications
American journal of roentgenology (1976), Vol.203(2), pp.253-260
08/01/2014
DOI: 10.2214/AJR.14.12554
PMCID: PMC4490786
PMID: 25055256
Abstract
OBJECTIVE. A significant challenge facing traditional cancer therapies is their propensity to significantly harm normal tissue. The recent clinical success of targeting therapies by attaching them to antibodies that are specific to tumor-restricted biomarkers marks a new era of cancer treatments.
CONCLUSION. In this article, we highlight the recent developments in alpha-particle therapy that have enabled investigators to exploit this highly potent form of therapy by targeting tumor-restricted molecular biomarkers.
Details
- Title: Subtitle
- Molecular Targeted alpha-Particle Therapy for Oncologic Applications
- Creators
- Thaddeus J. Wadas - Wake Forest UniversityDarpan N. Pandya - Wake Forest UniversityKiran Kumar Solingapuram Sai - Wake Forest Sch Med, Dept Radiol, Winston Salem, NC 27157 USAAkiva Mintz - Wake Forest Baptist Medical Center
- Resource Type
- Journal article
- Publication Details
- American journal of roentgenology (1976), Vol.203(2), pp.253-260
- DOI
- 10.2214/AJR.14.12554
- PMID
- 25055256
- PMCID
- PMC4490786
- NLM abbreviation
- AJR Am J Roentgenol
- ISSN
- 0361-803X
- eISSN
- 1546-3141
- Publisher
- Amer Roentgen Ray Soc
- Number of pages
- 8
- Grant note
- P30CA012197 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) 124443-MRSG-13-121-01-CDD / American Cancer Society W81XWH-13-1-0125 / Department of Defense; United States Department of Defense
- Language
- English
- Date published
- 08/01/2014
- Academic Unit
- Radiology; Radiation Oncology
- Record Identifier
- 9984313083202771
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