Molecular correlates of spontaneous activity in non-human primates

Amanda C Mitchell; Georgina Aldridge; Shawn Kohler; Greg Stanton; Elinor Sullivan; Krassimira Garbett; Gabor Faludi; Károly Mirnics; Judy L Cameron; William Greenough

doi:10.1007/s00702-010-0483-7

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Molecular correlates of spontaneous activity in non-human primates

Journal article

Peer reviewed

Molecular correlates of spontaneous activity in non-human primates

Amanda C Mitchell, Georgina Aldridge, Shawn Kohler, Greg Stanton, Elinor Sullivan, Krassimira Garbett, Gabor Faludi, Károly Mirnics, Judy L Cameron and William Greenough

Journal of neural transmission (Vienna, Austria : 1996), Vol.117(12), pp.1353-1358

12/2010

DOI: 10.1007/s00702-010-0483-7

PMCID: PMC3649869

PMID: 20838826

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https://www.ncbi.nlm.nih.gov/pmc/articles/3649869View

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Abstract

In our monkey model, cortical ARC and BDNF expressions were strongly correlated with spontaneous physical activity. The expressions of ARC and BDNF were inversely correlated with serum CRP levels, suggesting that CRP could be a putative peripheral marker of brain resiliency.

Gene Expression

CRP

ARC

Physical activity

BDNF

Motor cortex

Details

Title: Subtitle: Molecular correlates of spontaneous activity in non-human primates
Creators: Amanda C Mitchell - Department of Psychiatry, Vanderbilt University, 8130A MRB III, 465 21st Avenue South, Nashville, 37232, USA
Georgina Aldridge - Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Shawn Kohler - Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Greg Stanton - Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Elinor Sullivan - Oregon National Primate Research Center, Beaverton, OR, USA
Krassimira Garbett - Department of Psychiatry, Vanderbilt University, 8130A MRB III, 465 21st Avenue South, Nashville, 37232, USA
Gabor Faludi - Department of Psychiatry, Semmelweis University, Budapest, Hungary
Károly Mirnics - Department of Psychiatry, Vanderbilt University, 8130A MRB III, 465 21st Avenue South, Nashville, 37232, USA
Judy L Cameron - Oregon National Primate Research Center, Beaverton, OR, USA
William Greenough - Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Resource Type: Journal article
Publication Details: Journal of neural transmission (Vienna, Austria : 1996), Vol.117(12), pp.1353-1358
DOI: 10.1007/s00702-010-0483-7
PMID: 20838826
PMCID: PMC3649869
NLM abbreviation: J Neural Transm (Vienna)
ISSN: 0300-9564
eISSN: 1435-1463
Grant note: R01 MH079299 || MH / National Institute of Mental Health : NIMH R01 MH067234 || MH / National Institute of Mental Health : NIMH P30 HD015052 || HD / National Institute of Child Health & Human Development : NICHD
Language: English
Date published: 12/2010
Academic Unit: Neurology; Iowa Neuroscience Institute
Record Identifier: 9984020604402771

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