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Molecular mechanisms of B-lymphocyte transformation by Epstein–Barr virus
Journal article   Peer reviewed

Molecular mechanisms of B-lymphocyte transformation by Epstein–Barr virus

Gail A Bishop and Lisa K Busch
Microbes and Infection, Vol.4(8), pp.853-857
2002
DOI: 10.1016/S1286-4579(02)01605-2
PMID: 12270732

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Abstract

The B-lymphotropic virus Epstein–Barr virus (EBV) has been implicated in the pathogenesis of B-cell malignancies, particularly in immunodeficient individuals. This review provides a brief overview of the EBV-encoded proteins involved in B-cell transformation, and the current state of knowledge about their roles in this process.
B lymphocyte Signal transduction Cell transformation Lymphoma Epstein–Barr virus

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