Journal article
Molecular mechanisms of CD40 signaling
Archivum Immunologiae et Therapiae Experimentalis, Vol.49(2), pp.129-137
2001
PMID: 11348017
Abstract
CD40, a member of the growing tumor necrosis factor receptor (TNF-R) family of molecules, functions as a transmembrane signal receptor in both hematopoietic and non-hematopoietic cell types, although its physiological roles are less well understood in the latter. Much has been learned over the past decade about the role of CD40 signaling in various cellular functions. In addition, some of the molecular events which occur subsequent to CD40 engagement have been characterized, although much remains to be understood. This review will summarize the known important biological roles of CD40, and discuss what is currently known about how CD40 signals.
Details
- Title: Subtitle
- Molecular mechanisms of CD40 signaling
- Creators
- G A Bishop - Department of Microbiology, The University of Iowa, Iowa City 52240, USA. gail-bishop@uiowa.eduB S Hostager
- Resource Type
- Journal article
- Publication Details
- Archivum Immunologiae et Therapiae Experimentalis, Vol.49(2), pp.129-137
- Publisher
- Switzerland
- PMID
- 11348017
- ISSN
- 0004-069X
- eISSN
- 1661-4917
- Language
- English
- Date published
- 2001
- Academic Unit
- Microbiology and Immunology; President
- Record Identifier
- 9984001110102771
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