Journal article
Molecular, neuromuscular, and recovery responses to light versus heavy resistance exercise in young men
Physiological reports, Vol.5(18), pp.e13457-n/a
09/2017
DOI: 10.14814/phy2.13457
PMCID: PMC5617935
PMID: 28963127
Abstract
Recent evidence suggests that resistance training with light or heavy loads to failure results in similar adaptations. Herein, we compared how both training modalities affect the molecular, neuromuscular, and recovery responses following exercise. Resistance-trained males (mean ± SE: 22 ± 2 years, 84.8 ± 9.0 kg, 1.79 ± 0.06 m;
= 15) performed a crossover design of four sets of leg extensor exercise at 30% (light RE) or 80% (heavy RE) one repetition maximum (1RM) to repetition failure, and heavy RE or light RE 1 week later. Surface electromyography (EMG) was monitored during exercise, and vastus lateralis muscle biopsies were collected at baseline (PRE), 15 min (15mPOST), and 90 min following RE (90mPOST) for examination of molecular targets and fiber typing. Isokinetic dynamometry was also performed before (PRE), immediately after (POST), and 48 h after (48hPOST) exercise. Dependent variables were analyzed using repeated measures ANOVAs and significance was set at
≤ 0.05. Repetitions completed were greater during light RE (
< 0.01), while EMG amplitude was greater during heavy RE (
≤ 0.01). POST isokinetic torque was reduced following light versus heavy RE (
< 0.05). Postexercise expression of mRNAs and phosphoproteins associated with muscle hypertrophy were similar between load conditions. Additionally, p70s6k (Thr389) phosphorylation and fast-twitch fiber proportion exhibited a strong relationship after both light and heavy RE (
> 0.5). While similar mRNA and phosphoprotein responses to both modalities occurred, we posit that heavy RE is a more time-efficient training method given the differences in total repetitions completed, lower EMG amplitude during light RE, and impaired recovery response after light RE.
Details
- Title: Subtitle
- Molecular, neuromuscular, and recovery responses to light versus heavy resistance exercise in young men
- Creators
- Cody T Haun - University of MichiganPetey W Mumford - University of MichiganPaul A Roberson - University of MichiganMatthew A Romero - University of MichiganChristopher B Mobley - University of MichiganWesley C Kephart - University of MichiganRichard G Anderson - University of MichiganRyan J Colquhoun - Oklahoma State UniversityTyler W D Muddle - Oklahoma State UniversityMichael J Luera - Oklahoma State UniversityCameron S Mackey - Oklahoma State UniversityDavid D Pascoe - University of MichiganKaelin C Young - Edward Via College of Osteopathic MedicineJeffrey S Martin - Edward Via College of Osteopathic MedicineJason M DeFreitas - Oklahoma State UniversityNathaniel D M Jenkins - Oklahoma State UniversityMichael D Roberts - Edward Via College of Osteopathic Medicine
- Resource Type
- Journal article
- Publication Details
- Physiological reports, Vol.5(18), pp.e13457-n/a
- DOI
- 10.14814/phy2.13457
- PMID
- 28963127
- PMCID
- PMC5617935
- NLM abbreviation
- Physiol Rep
- eISSN
- 2051-817X
- Grant note
- name: FutureCeuticals Inc.; name: Maximum Human Performance
- Language
- English
- Date published
- 09/2017
- Academic Unit
- Center for Social Science Innovation; Injury Prevention Research Center; Health, Sport, and Human Physiology
- Record Identifier
- 9984259397402771
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