Journal article
Mondini dysplasia and congenital cytomegalovirus infection
The Journal of pediatrics, Vol.124(1), pp.71-78
1994
DOI: 10.1016/S0022-3476(94)70256-X
PMID: 8283378
Abstract
We report a case of bilateral temporal bone anomalies in a child with symptomatic congenital cytomegalovirus infection and severe, bilateral sensorineural hearing loss identified at 3 months of age. High-resolution temporal bone computed tomography (HRCT) revealed bilateral findings of a short, malformed cochlea lacking an interscalar septum, a short and wide internal auditory canal, and an enlarged vestibular aqueduct, features diagnostic of bilateral Mondini dysplasia. To determine the importance of this observation, we completed HRCT in five additional children between 7 months and 9 years of age who had evidence of symptomatic congenital cytomegalovirus infection. One child with profound sensorineural hearing loss had severe bilateral temporal bone dysplasia with a small cochlea lacking an interscalar septum, an abnormal vestibule, and a large cochlear aqueduct. Of the remaining four children, hearing thresholds ranged from normal to profoundly decreased, but their HRCT scans were normal to visual inspection. When inner ear dimensions of these temporal bones were compared with norms established by Pappas and co-workers, however, seven of the eight ears had short cochleas and narrow lateral semicircular canals, and three ears had short or narrow vestibules. These results indicate that congenital cytomegalovirus infection may cause anomalies or growth disturbances of the temporal bone. (J P
EDIATR 1994;124:71-8)
Details
- Title: Subtitle
- Mondini dysplasia and congenital cytomegalovirus infection
- Creators
- Nancy M. Bauman - University of IowaLinda J. Kirby-Keyser - University of IowaKenneth D. Dolan - University of IowaDavid Wexler - University of IowaBruce J. Gantz - University of IowaBrian F. McCabe - University of IowaJames F. Bale - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of pediatrics, Vol.124(1), pp.71-78
- Publisher
- Mosby, Inc
- DOI
- 10.1016/S0022-3476(94)70256-X
- PMID
- 8283378
- ISSN
- 0022-3476
- eISSN
- 1097-6833
- Language
- English
- Date published
- 1994
- Academic Unit
- Neurosurgery; Otolaryngology
- Record Identifier
- 9984304039302771
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