Monitoring Response to Combinatorial Immunotherapies by Tracking both T Cells and Natural Killer Cells In Vivo via ImmunoPET-Raman Multimodal Gold Nanostars

We acknowledge Ben Hackel for providing facilities support for PET/CT imaging (Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455). We acknowledge Shawn Rigby and the Iowa State University flow cytometry core for running flow cytometry (Iowa State University, Ames, IA 50011) and Rachael Derscheid and the Iowa State University Veterinary Diagnostic laboratories for spleen immunohistochemistry (Iowa State University, Ames, IA 50011). G.P.C., S.K., and A.M. acknowledge support from the National Institutes of Health (NIH) award R01EB029756-01A1. S.U. acknowledges support from the National Science Foundation Award CMMI-2223689. R.B. acknowledges support from the Jean H. Steffenson Endowed Chair, NIH Award R01EB029756-01A1, and NSF Award CMMI-2223689. A.E.V. acknowledges support from NIH Award R37 CA233770 and the Department of Defense Award W81XWH2210019. The authors acknowledge the use of the University of Iowa's Small Animal Imaging Core Facility, which operates under the auspices of the Iowa Institute for Biomedical Imaging and the Department of Radiology. This work was supported by the resources and staff at the University of Minnesota University Imaging Centers (UIC) under Award SCR_020997.