Journal article
More Effective Nanomedicines through Particle Design
Small (Weinheim an der Bergstrasse, Germany), Vol.7(14), pp.1919-1931
07/18/2011
DOI: 10.1002/smll.201100442
PMCID: PMC3136586
PMID: 21695781
Abstract
Nanomedicine is an emerging field that applies concepts in nanotechnology to develop novel diagnostics and therapies. Physical and chemical properties of particles, including size, shape, modulus, surface charge and surface chemistry, play an important role in determining particle-cell interactions, cellular trafficking mechanisms, biodistribution, and pharmacokinetics. This discussion focuses on both nanoparticles and microparticles since microparticles can also provide many insights for the development of drug carriers and possess advantages over nanoparticles in certain applications. This review covers recent major advancement in the nanomedicine field and also highlights studies using the PRINT technology. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Details
- Title: Subtitle
- More Effective Nanomedicines through Particle Design
- Creators
- Jin Wang - University of North Carolina at Chapel HillJames D. Byrne - University of North Carolina at Chapel HillMary E. Napier - University of North Carolina at Chapel HillJoseph M. DeSimone - University of North Carolina at Chapel Hill
- Resource Type
- Journal article
- Publication Details
- Small (Weinheim an der Bergstrasse, Germany), Vol.7(14), pp.1919-1931
- DOI
- 10.1002/smll.201100442
- PMID
- 21695781
- PMCID
- PMC3136586
- NLM abbreviation
- Small
- ISSN
- 1613-6810
- eISSN
- 1613-6829
- Publisher
- WILEY-VCH Verlag
- Number of pages
- 13
- Language
- English
- Date published
- 07/18/2011
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiation Oncology
- Record Identifier
- 9984274857802771
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