Journal article
Morphological evidence for brainstem involvement in infantile autism
Biological psychiatry (1969), Vol.24(5), pp.578-586
1988
DOI: 10.1016/0006-3223(88)90168-0
PMID: 3167146
Abstract
Previous neurophysiological and neuroanatomic studies suggest brainstem dysfunction in infantile autism. Therefore, we investigated the brainstem structure of autistic patients by planimetric analysis of midsagittal magnetic resonance imaging scans. We found the entire brainstem and one component—the pons—to be statistically significantly smaller in the autistic group when compared with medical controls. We also noted no correlation between brainstem size and age in the autistic group—a correlation that was found in the control group. These data present morphological evidence of brainstem involvement in the infantile autism syndrome.
Details
- Title: Subtitle
- Morphological evidence for brainstem involvement in infantile autism
- Creators
- Gary R Gaffney - From the Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of Kansas Hospital and College of Health Sciences, Kansas City, KS, USASamuel Kuperman - the Department of Psychiatry, Division of Child Psychiatry, University of Iowa College of Medicine, Iowa City, IW, USALuke Y Tsai - From the Department of Psychiatry, Division of Child and Adolescent Psychiatry, University of Kansas Hospital and College of Health Sciences, Kansas City, KS, USASusan Minchin - the Department of Psychiatry, Division of Child Psychiatry, University of Iowa College of Medicine, Iowa City, IW, USA
- Resource Type
- Journal article
- Publication Details
- Biological psychiatry (1969), Vol.24(5), pp.578-586
- Publisher
- Elsevier Inc
- DOI
- 10.1016/0006-3223(88)90168-0
- PMID
- 3167146
- ISSN
- 0006-3223
- eISSN
- 1873-2402
- Language
- English
- Date published
- 1988
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984003407202771
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