Journal article
Morphometry of the superior temporal plane in schizophrenia: relationship to clinical correlates
The journal of neuropsychiatry and clinical neurosciences, Vol.16(3), pp.284-294
2004
DOI: 10.1176/appi.neuropsych.16.3.284
PMID: 15377735
Abstract
A magnetic-resonance-imaging-based method of cortical parcellation was used to evaluate the morphology of the superior temporal plane and its subregions (Heschl's gyrus [HG], planum temporale [PT], and planum polare [PP]) in a group of 30 patients with schizophrenia versus a matched group of healthy subjects. Right HG volume was significantly reduced in patients compared with control subjects. Each subregion showed a unique set of structure/function relationships: reduced volumes of the HG were associated with greater duration of illness; reduced volumes of the PT were associated with positive symptoms; and in most contrast, elevated volumes of the PP were associated with cumulative neuroleptic exposure.
Details
- Title: Subtitle
- Morphometry of the superior temporal plane in schizophrenia: relationship to clinical correlates
- Creators
- Benedicto Crespo-Facorro - Mental Health-Clinical Research Center, Department of Psychiatry, College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USAJae-Jin KimEran ChemerinskiVincent MagnottaNancy C AndreasenPeg Nopoulos
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.16(3), pp.284-294
- Publisher
- United States
- DOI
- 10.1176/appi.neuropsych.16.3.284
- PMID
- 15377735
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Grant note
- MH-19113 / NIMH NIH HHS MH-CRC43271 / NIMH NIH HHS MH-31593 / NIMH NIH HHS MH-40856 / NIMH NIH HHS
- Language
- English
- Date published
- 2004
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Neurology; Radiology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984003476702771
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