Motor Neuron and Pancreas Homeobox 1 Mutations in Patients with Familial Neuroendocrine Tumors

Aaron T Scott; Jonathon B Tessmann; Terry Braun; Benjamin W Darbro; Patrick Breheny; Andrew M Bellizzi; Joseph S Dillon; Thomas M O'Dorisio

doi:10.1016/j.jamcollsurg.2018.07.169

Journal article

Motor Neuron and Pancreas Homeobox 1 Mutations in Patients with Familial Neuroendocrine Tumors

Aaron T Scott, Jonathon B Tessmann, Terry Braun, Benjamin W Darbro, Patrick Breheny, Andrew M Bellizzi, Joseph S Dillon and Thomas M O'Dorisio

Journal of the American College of Surgeons, Vol.227(4), pp.S85-S86

10/2018

DOI: 10.1016/j.jamcollsurg.2018.07.169

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Abstract

Neuroendocrine tumors (NETs) are rare neoplasms that may be associated with hereditary cancer syndromes, such as multiple endocrine neoplasia type 1 (MEN1) and von Hippel-Lindau (VHL). However, NETs have also been observed at higher than expected rates in families without known familial cancer syndromes. We investigated the genetic basis of familial NETs using exome sequencing.

Details

Title: Subtitle: Motor Neuron and Pancreas Homeobox 1 Mutations in Patients with Familial Neuroendocrine Tumors
Creators: Aaron T Scott
Jonathon B Tessmann
Terry Braun
Benjamin W Darbro
Patrick Breheny
Andrew M Bellizzi
Joseph S Dillon
Thomas M O'Dorisio
Resource Type: Journal article
Publication Details: Journal of the American College of Surgeons, Vol.227(4), pp.S85-S86
DOI: 10.1016/j.jamcollsurg.2018.07.169
ISSN: 1072-7515
eISSN: 1879-1190
Language: English
Date published: 10/2018
Academic Unit: Internal Medicine; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center; Endocrinology and Metabolism; Biostatistics; Pathology; Roy J. Carver Department of Biomedical Engineering; Medical Genetics and Genomics
Record Identifier: 9984200019702771

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