Mouse hepatitis virus and herpes simplex virus move along different CNS pathways

S Perlman; E Barnett; G Jacobsen

doi:10.1007/978-1-4615-2996-5_48

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Mouse hepatitis virus and herpes simplex virus move along different CNS pathways

Journal article

Peer reviewed

Mouse hepatitis virus and herpes simplex virus move along different CNS pathways

S Perlman, E Barnett and G Jacobsen

Advances in experimental medicine and biology, Vol.342, pp.313-318

1993

DOI: 10.1007/978-1-4615-2996-5_48

PMID: 7516106

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Abstract

The spread of mouse hepatitis virus, strain JHM and herpes simplex virus type 1 in the central nervous system after inoculation into the nares and main olfactory bulb has been examined. The results show that each virus infects a subset of the possible connections of the olfactory bulb and that the subset infected by each virus is different. Thus, both viruses will be useful for studying the neuroanatomic connections of the olfactory bulb, and possibly for functional analyses as well.

Axonal Transport

Trigeminal Nerve - microbiology

Brain - microbiology

Simplexvirus - physiology

Specific Pathogen-Free Organisms

Species Specificity

Mice, Inbred C57BL

Dental Pulp - microbiology

Administration, Intranasal

Murine hepatitis virus - physiology

Injections

Locus Coeruleus - microbiology

Animals

Brain - ultrastructure

Mice

Mice, Inbred BALB C

Olfactory Bulb - microbiology

Olfactory Pathways - microbiology

Details

Title: Subtitle: Mouse hepatitis virus and herpes simplex virus move along different CNS pathways
Creators: S Perlman - Department of Pediatrics, College of Dentistry, University of Iowa, Iowa City 52242
E Barnett
G Jacobsen
Resource Type: Journal article
Publication Details: Advances in experimental medicine and biology, Vol.342, pp.313-318
DOI: 10.1007/978-1-4615-2996-5_48
PMID: 7516106
NLM abbreviation: Adv Exp Med Biol
ISSN: 0065-2598
Publisher: United States
Grant note: NS24401 / NINDS NIH HHS
Language: English
Date published: 1993
Academic Unit: Preventive and Community Dentistry; Microbiology and Immunology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Infectious Disease (Pediatrics)
Record Identifier: 9983777348902771

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