Journal article
Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis
Nucleus, Vol.8(6), pp.613-624
11/02/2017
DOI: 10.1080/19491034.2017.1358329
PMCID: PMC5788555
PMID: 28892406
Abstract
Meiosis is a specialized cellular division occurring in organisms capable of sexual reproduction that leads to the formation of gametes containing half of the original chromosome number. During the earliest stage of meiosis, prophase I, pairing of homologous chromosomes is achieved in preparation for their proper distribution in the coming divisions. An important question is how do homologous chromosomes find each other and establish pairing interactions. Early studies demonstrated that chromosomes are dynamic in nature and move during this early stage of meiosis. More recently, there have been several studies across different models showing the conserved nature and importance of this chromosome movement, as well as the key components involved in chromosome movement. This review will cover these major findings and also introduce unexamined areas of regulation in meiotic prophase I chromosome movement.
Details
- Title: Subtitle
- Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis
- Creators
- Benjamin Alleva - Department of Biology, The University of IowaSarit Smolikove - Department of Biology, The University of Iowa
- Resource Type
- Journal article
- Publication Details
- Nucleus, Vol.8(6), pp.613-624
- Publisher
- Taylor & Francis
- DOI
- 10.1080/19491034.2017.1358329
- PMID
- 28892406
- PMCID
- PMC5788555
- ISSN
- 1949-1034
- eISSN
- 1949-1042
- Language
- English
- Date published
- 11/02/2017
- Academic Unit
- Biology
- Record Identifier
- 9983992093602771
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