Journal article
Mpox, sexually transmitted infections and combination prevention: insights from a major cohort in Rio de Janeiro, Brazil
AIDS (London), Vol.38(13), pp.1845-1849
11/01/2024
DOI: 10.1097/QAD.0000000000003991
PMCID: PMC11424052
PMID: 39120535
Abstract
Objective:To evaluate the prevalence and characteristics of concurrent bacterial sexually transmitted infections (bSTIs) among individuals with mpox.Design:Prospective cohort study of participants aged 18 years or older with confirmed mpox conducted in Rio de Janeiro, Brazil. This cross-sectional analysis includes only participants who underwent bSTI testing at baseline between June 2022 and January 2024.Methods:Participants were offered testing for chlamydia/gonorrhea (NAAT, anorectal swabs) and syphilis (active diagnosis if VDRL >= 1/8). Baseline prevalence of bSTIs was calculated, and participant characteristics were described based on concomitant bSTI diagnosis (yes/no). Chi-squared/Fisher's tests were used for qualitative variables, and the Wilcoxon rank-sum test for quantitative variables.Results:Out of 634 enrolled participants, 538 (84.9%) were tested for STIs and included in this analysis, mostly cisgender men, aged 30-39 years with postsecondary education. Overall prevalence of concomitant bSTI was 37.3%, mainly syphilis, followed by chlamydia and gonorrhea. Half of the participants were living with HIV, and one third was on HIV pre-exposure prophylaxis. Concomitant bSTI diagnosis at the time of mpox assessment was associated with being aged 30-39 years, self-identifying as cisgender men, having HIV-positive status, reporting proctitis symptoms and reporting any STI in the past 12 months.Conclusions:Our data reveals a notable prevalence of concomitant bSTIs among participants with confirmed mpox at a prominent infectious diseases' referral center in Rio de Janeiro, Brazil. These findings underscore the importance of integrating mpox into the differential diagnosis of anogenital manifestations and the promotion of combination prevention strategies within sexual healthcare services.
Details
- Title: Subtitle
- Mpox, sexually transmitted infections and combination prevention: insights from a major cohort in Rio de Janeiro, Brazil
- Creators
- Mayara S. T. Silva - Instituto Evandro ChagasThiago S. Torres - Instituto Evandro ChagasCarolina Coutinho - Instituto Evandro ChagasEmilia M. Jalil - Instituto Evandro ChagasCarolyn Yanavich - Instituto Evandro ChagasPedro S. Martins - Instituto Evandro ChagasMatheus O. Bastos - Instituto Evandro ChagasMaira B. Mesquita - Instituto Evandro ChagasAmanda Echeverria-Guevara - Instituto Evandro ChagasSandro Nazer - Instituto Evandro ChagasEduardo M. Peixoto - Instituto Evandro ChagasMarcela Terra - Instituto Evandro ChagasAna Lovetro - Instituto Evandro ChagasPaula P. S. Reges - Instituto Evandro ChagasMaria Roberta Meneguetti - Instituto Evandro ChagasRonaldo I. Moreira - Instituto Evandro ChagasFlavia C. S. Lessa - Instituto Evandro ChagasBrenda Hoagland - Instituto Evandro ChagasEstevao P. Nunes - Instituto Evandro ChagasSandra Wagner Cardoso - Instituto Evandro ChagasValdilea G. Veloso - Instituto Evandro ChagasBeatriz Grinsztejn - Instituto Evandro ChagasINI Fiocruz Mpox Study Group
- Resource Type
- Journal article
- Publication Details
- AIDS (London), Vol.38(13), pp.1845-1849
- DOI
- 10.1097/QAD.0000000000003991
- PMID
- 39120535
- PMCID
- PMC11424052
- NLM abbreviation
- AIDS
- ISSN
- 0269-9370
- eISSN
- 1473-5571
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 5
- Grant note
- Brazilian Ministry of Health National Institute of Infectious Diseases Evandro Chagas, Fiocruz
- Language
- English
- Date published
- 11/01/2024
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984772265402771
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