Mucopolysaccharidosis: radiographic findings in a series of 16 cases

Dmitry José de Santana Sarmento; Sérgio Henrique Gonçalves de Carvalho; Saulo Leonardo Sousa Melo; Fátima Roneiva Alves Fonseca; Denise Nóbrega Diniz; Patrícia Meira Bento; Germana de Queiroz Tavares Borges Mesquita; Daniela Pita de Melo

doi:10.1016/j.oooo.2015.08.009

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Mucopolysaccharidosis: radiographic findings in a series of 16 cases

Journal article

Peer reviewed

Mucopolysaccharidosis: radiographic findings in a series of 16 cases

Dmitry José de Santana Sarmento, Sérgio Henrique Gonçalves de Carvalho, Saulo Leonardo Sousa Melo, Fátima Roneiva Alves Fonseca, Denise Nóbrega Diniz, Patrícia Meira Bento, Germana de Queiroz Tavares Borges Mesquita and Daniela Pita de Melo

Oral surgery, oral medicine, oral pathology and oral radiology, Vol.120(6), pp.e240-e246

12/01/2015

DOI: 10.1016/j.oooo.2015.08.009

PMID: 26455293

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Abstract

To investigate the radiographic findings of mucopolysaccharidoses (MPS) on panoramic radiographs in a series of 16 patients. This retrospective cross-sectional study included panoramic radiographs of 16 patients with cytogenetically diagnosed MPS. Two blinded, previously calibrated observers evaluate the presence or absence of the following features: type of dentition; stage of dental age in comparison with chronologic age; delayed exfoliation of deciduous teeth; supernumerary teeth; teeth impaction; enlarged, cyst-like dental crypt; hypercementosis; taurodontism; generalized enamel hypoplasia; enlargement of the bone marrow spaces; thinning of cortical bone; unusual morphology of condyles; and flattening of the condylar head. The final sample was composed of 8 MPS IV, 7 MPS VI, and 1 MPS I cases. All patients presented unusual morphology of condyles. Cyst-like dental crypt (75%), taurodontism, and teeth impaction (68.75% each) were also overall common findings. Generalized enamel hypoplasia was exclusively identified in patients with MPS IV (75% of those patients). Radiographic features of oral and maxillofacial manifestations in patients with MPS frequently encountered by dentists may help recognize the disorder. However, because of sample size limitations, it was not possible to infer any statistical relationship between the radiographic features and the types of MPS.

Adolescent

Adult

Child

Child, Preschool

Cross-Sectional Studies

Female

Humans

Infant

Male

Mouth Diseases - diagnostic imaging

Mucopolysaccharidoses - diagnostic imaging

Radiography, Panoramic

Retrospective Studies

Details

Title: Subtitle: Mucopolysaccharidosis: radiographic findings in a series of 16 cases
Creators: Dmitry José de Santana Sarmento - Universidade Estadual da Paraíba
Sérgio Henrique Gonçalves de Carvalho - Universidade Estadual da Paraíba
Saulo Leonardo Sousa Melo - University of Iowa
Fátima Roneiva Alves Fonseca - Department of Dentistry, Integrated Colleges of Patos, Patos, Paraíba, Brazil
Denise Nóbrega Diniz - Universidade Estadual da Paraíba
Patrícia Meira Bento - Universidade Estadual da Paraíba
Germana de Queiroz Tavares Borges Mesquita - Department of Dentistry, Integrated Colleges of Patos, Patos, Paraíba, Brazil
Daniela Pita de Melo - Universidade Estadual da Paraíba
Resource Type: Journal article
Publication Details: Oral surgery, oral medicine, oral pathology and oral radiology, Vol.120(6), pp.e240-e246
DOI: 10.1016/j.oooo.2015.08.009
PMID: 26455293
NLM abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol
ISSN: 2212-4403
eISSN: 2212-4411
Language: English
Date published: 12/01/2015
Academic Unit: Radiology; Oral Pathology, Radiology and Medicine
Record Identifier: 9985244559502771

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