Journal article
Multi-component nanorods for vaccination applications
Nanotechnology, Vol.16(4), pp.484-487
04/01/2005
DOI: 10.1088/0957-4484/16/4/025
Abstract
Immune responses from Au/Ni nanorods prepared by electrochemical deposition in alumina templates are evaluated in C57BL/6 mice. When the nanorods are bombarded into skin, they generate a strong CD8 T-cell and antibody response. When pcDNA3 is bound to the Ni segment of the nanorod, it provides a strong immunostimulatory adjuvant effect to the antigen bound on the Au segment.
Details
- Title: Subtitle
- Multi-component nanorods for vaccination applications
- Creators
- A K SalemC F HungT W KimT C WuP C SearsonK W Leong
- Resource Type
- Journal article
- Publication Details
- Nanotechnology, Vol.16(4), pp.484-487
- DOI
- 10.1088/0957-4484/16/4/025
- ISSN
- 0957-4484
- eISSN
- 1361-6528
- Language
- English
- Date published
- 04/01/2005
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Dental Research; Chemical and Biochemical Engineering
- Record Identifier
- 9983985850802771
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