Journal article
MultiCenter Reliability of Diffusion Tensor Imaging
Brain connectivity, Vol.2(6), pp.345-355
12/01/2012
DOI: 10.1089/brain.2012.0112
PMCID: PMC3623569
PMID: 23075313
Abstract
A number of studies are now collecting diffusion tensor imaging (DTI) data across sites. While the reliability of anatomical images has been established by a number of groups, the reliability of DTI data has not been studied as extensively. In this study, five healthy controls were recruited and imaged at eight imaging centers. Repeated measures were obtained across two imaging protocols allowing intra-subject and inter-site variability to be assessed. Regional measures within white matter were obtained for standard rotationally invariant measures: fractional anisotropy, mean diffusivity, radial diffusivity, and axial diffusivity. Intra-subject coefficient of variation (CV) was typically <1% for all scalars and regions. Inter-site CV increased to ∼1%–3%. Inter-vendor variation was similar to inter-site variability. This variability includes differences in the actual implementation of the sequence.
Details
- Title: Subtitle
- MultiCenter Reliability of Diffusion Tensor Imaging
- Creators
- Vincent A Magnotta - 2Department of Psychiatry, The University of Iowa, Iowa City, IowaJoy T Matsui - 3John A. Burns School of Medicine, The University of Hawaii, Honolulu, HawaiiDawei Liu - 4Department of Biostatistics, The University of Iowa, Iowa City, IowaHans J Johnson - 2Department of Psychiatry, The University of Iowa, Iowa City, IowaJeffrey D Long - 2Department of Psychiatry, The University of Iowa, Iowa City, IowaBradley D Bolster - 5MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Rochester, MinnesotaBryon A Mueller - 6Department of Psychiatry, The University of Minnesota, Minneapolis, MinnesotaKelvin Lim - 6Department of Psychiatry, The University of Minnesota, Minneapolis, MinnesotaSusumu Mori - 7Department of Radiology, Johns Hopkins University, Baltimore, MarylandKarl G Helmer - 8Department of Radiology, Massachusetts General Hospital, Charlestown, MassachusettsJessica A Turner - 9MIND Research Network, Albuquerque, New MexicoSarah Reading - 12Department of Psychiatry and Neurosciences, University of South Florida, Tampa, FloridaMark J Lowe - 13Department of Radiology, Cleveland Clinic Foundation, Cleveland, OhioElizabeth Aylward - 14Department of Radiology, Seattle Children's Hospital, Seattle, WashingtonLaura A Flashman - 15Department of Psychiatry, Dartmouth Medical School, Hanover, New HampshireGreg Bonett - 16The University of California Los Angeles, Los Angeles, CaliforniaJane S Paulsen - 2Department of Psychiatry, The University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Brain connectivity, Vol.2(6), pp.345-355
- DOI
- 10.1089/brain.2012.0112
- PMID
- 23075313
- PMCID
- PMC3623569
- NLM abbreviation
- Brain Connect
- ISSN
- 2158-0014
- eISSN
- 2158-0022
- Publisher
- Mary Ann Liebert, Inc
- Language
- English
- Date published
- 12/01/2012
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Psychiatry; Psychological and Brain Sciences; Iowa Neuroscience Institute; Biostatistics
- Record Identifier
- 9984003997602771
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