Multifractal analysis of nonlinear complexity of sacral skin blood flow oscillations in older adults

Fuyuan Liao; Bryan D. Struck; Margo MacRobert; Yih-Kuen Jan

doi:10.1007/s11517-011-0775-6

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$Multifractal analysis of nonlinear complexity of sacral skin blood flow oscillations in older adults$

Journal article

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Multifractal analysis of nonlinear complexity of sacral skin blood flow oscillations in older adults

Fuyuan Liao, Bryan D. Struck, Margo MacRobert and Yih-Kuen Jan

Medical & biological engineering & computing, Vol.49(8), pp.925-934

08/01/2011

DOI: 10.1007/s11517-011-0775-6

PMCID: PMC3140590

PMID: 21487818

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https://www.ncbi.nlm.nih.gov/pmc/articles/3140590View

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Abstract

The objective of this study was to investigate the relationship between cutaneous vasodilatory function and nonlinear complexity of blood flow oscillations (BFO) in older people. A non-painful fast local heating protocol was applied to the sacral skin in 20 older subjects with various vasodilatory functions. Laser Doppler flowmetry was used to measure skin blood oscillations. The complexity of the characteristic frequencies (i.e., metabolic (0.0095-0.02 Hz), neurogenic (0.02-0.05 Hz), myogenic (0.05-0.15 Hz), respiratory (0.15-0.4 Hz), and cardiac (0.4-2 Hz)) of BFO was quantified using the multifractal detrended fluctuation analysis. Compared with the 65-75 years group, the complexity of metabolic BFO in the 75-85 years group was significantly lower at the baseline (P < 0.05) and the second peak (P < 0.001). Compared with baseline BFO, subjects in the 65-75 years group had a significant increase in the complexity of metabolic BFO (P < 0.01) in response to local heating; while subjects in the 75-85 years group did not. Our findings support the use of multifractal analysis to assess aging-related microvascular dysfunction.

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Details

Title: Subtitle: Multifractal analysis of nonlinear complexity of sacral skin blood flow oscillations in older adults
Creators: Fuyuan Liao - University of Oklahoma Health Sciences Center
Bryan D. Struck - University of Oklahoma Health Sciences Center
Margo MacRobert - University of Oklahoma Health Sciences Center
Yih-Kuen Jan - University of Oklahoma
Resource Type: Journal article
Publication Details: Medical & biological engineering & computing, Vol.49(8), pp.925-934
DOI: 10.1007/s11517-011-0775-6
PMID: 21487818
PMCID: PMC3140590
NLM abbreviation: Med Biol Eng Comput
ISSN: 0140-0118
eISSN: 1741-0444
Publisher: Springer Nature
Number of pages: 10
Grant note: R21HD065073 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) R21HD065073 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
Language: English
Date published: 08/01/2011
Academic Unit: Internal Medicine
Record Identifier: 9984695678602771

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