Journal article
Multifunctional nanorods for biomedical applications
Pharmaceutical research, Vol.24(12), pp.2335-2352
12/2007
DOI: 10.1007/s11095-007-9380-7
PMID: 17684708
Abstract
Multifunctional nanorods have shown significant potential in a wide range of biomedical applications. Nanorods can be synthesized by a top down or bottom-up approach. The bottom-up approach commonly utilizes a template deposition methodology. A variety of metal segments can easily be incorporated into the nanorods. This permits high degrees of chemical and dimensional control. High aspect-ratio nanorods have a large surface area for functionalization. By varying the metal segments in the nanorods, spatial control over the binding of functional biomolecules that correspond with the unique surface chemistry of the metal segment can be achieved. Functionalized multicomponent nanorods are utilized in applications ranging from multiplexing, protein sensing, glucose sensing, imaging, biomolecule-associated nanocircuits, gene delivery and vaccinations.
Details
- Title: Subtitle
- Multifunctional nanorods for biomedical applications
- Creators
- Megan E Pearce - Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa 52242, USAJessica B MelankoAliasger K Salem
- Resource Type
- Journal article
- Publication Details
- Pharmaceutical research, Vol.24(12), pp.2335-2352
- DOI
- 10.1007/s11095-007-9380-7
- PMID
- 17684708
- NLM abbreviation
- Pharm Res
- ISSN
- 0724-8741
- eISSN
- 1573-904X
- Publisher
- United States
- Language
- English
- Date published
- 12/2007
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Dental Research; Chemical and Biochemical Engineering
- Record Identifier
- 9983985845202771
Metrics
15 Record Views