Journal article
Multiparameter Analysis of Titanium Vocal Fold Medializing Implant in an Excised Larynx Model
Annals of otology, rhinology & laryngology, Vol.119(2), pp.125-132
02/01/2010
DOI: 10.1177/000348941011900210
PMCID: PMC2907079
PMID: 20336924
Abstract
Objectives: We evaluated the efficacy of the titanium vocal fold medializing implant (TVFMI) for the treatment of unilateral vocal fold paralysis (UVFP) on the basis of acoustic , aerodynamic, and mucosal wave measurements in and excised larynx setup.
Methods: Measurements were recorded on 8 excised canine larynges with simulated UVFP before and after medialization with a TVFMI.
Results: The phonation threshold flow (p < 0.001) and phonation threshold power (p = 0.008) decreased significantly after medialization. The phonation threshold pressure also decreased, but this difference was not significant (p = 0.081). Jitter (p = 0.005) and shimmer (p = 0.034) decreased significantly after medialization. The signal-to-noise ratio increased significantly (p = 0.05). Differences in mucosal wave characteristics were discernible but not significant. The phase difference between the normal and paralyzed vocal folds (p = 0.15) and the amplitude of the paralyzed vocal fold (p = 0.78) decreased. The glottal gap decreased significantly (p = 0.004).
Conclusions: The TVFMI was effective in achieving vocal fold medialization, improving vocal aerodynamic and acoustic characteristics of phonation significantly and mucosal wave characteristics discernibly. This study provides objective, quantitative support for the use of the TVFMI in improving vocal function in patients with UVFP.
Details
- Title: Subtitle
- Multiparameter Analysis of Titanium Vocal Fold Medializing Implant in an Excised Larynx Model
- Creators
- Rachel E. Witt - University of Wisconsin–MadisonMatthew R. Hoffman - University of Wisconsin School of Medicine and Public HealthGerhard Friedrich - Medical University of GrazAdam L. Rieves - University of Wisconsin School of Medicine and Public HealthBenjamin J. Schoepke - University of Wisconsin–MadisonJack J. Jiang - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Annals of otology, rhinology & laryngology, Vol.119(2), pp.125-132
- DOI
- 10.1177/000348941011900210
- PMID
- 20336924
- PMCID
- PMC2907079
- NLM abbreviation
- Ann Otol Rhinol Laryngol
- ISSN
- 0003-4894
- eISSN
- 1943-572X
- Publisher
- Sage
- Number of pages
- 8
- Grant note
- R01DC008153 / NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD) R01 DC008153-03; R01 DC008153-04; R01 DC008153; R01 DC008153-02; R01 DC008153-01A2 / NIDCD NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Deafness & Other Communication Disorders (NIDCD)
- Language
- English
- Date published
- 02/01/2010
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984366372902771
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