Journal article
Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
Diabetology and metabolic syndrome, Vol.6(1), pp.89-89
08/21/2014
DOI: 10.1186/1758-5996-6-89
PMCID: PMC4153892
PMID: 25191526
Abstract
Background: The burden of diabetes in Lebanon requires well-targeted interventions for screening type 2 diabetes mellitus (T2DM) and prediabetes and prevention of risk factors. Newly recruited 998 Lebanese individuals, in addition to 7,292 already available, were studied to investigate the prevalence of diabetes, prediabetes and their associated risk factors. Methods. Participants had fasting blood sugar and glycohemoglobin tests in addition to a lipid profile. Clinical and demographic information were obtained from a detailed questionnaire. The relationship between T2DM, its risk factors, and its complications were tested. Comparisons of these risk factors among diabetics, healthy, and coronary artery disease (CAD) patients were performed. Results: The prevalence of T2DM significantly increased with increasing BMI (p < 0.0001). Exercise activity level negatively correlated with the disease (p = 0.002), whereas the prevalence of T2DM (p < 0.0001) and CAD family history (p = 0.006) positively correlated with the affection status. The mean levels of triglycerides and LDL-C were significantly higher in diabetics (1.87; 1.35) compared to individuals with prediabetes (1.63; 1.26) and unaffected controls (1.49; 1.19). People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). Other comorbid factors such as hypertension (p < 0.0001) and self-reported obesity (p < 0.0001) were highly associated with T2DM and prediabetes. Reproductive health of women showed a strong correlation between giving birth to a baby with a high weight and the occurrence of T2DM and prediabetes later in life (p < 0.0001). Retinopathy and peripheral neuropathy were significantly correlated with diabetes and prediabetes (p < 0.0001). Conclusions: The present study shows an alarming prevalence of diabetes and prediabetes in the studied subgroups representative of the Lebanese population.
Details
- Title: Subtitle
- Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
- Creators
- Michella Ghassibe-Sabbagh - Lebanese American UniversityMary Deeb - Lebanese American UniversityAngelique K Salloum - Lebanese American UniversityFrancis Mouzaya - Lebanese American UniversityMarc Haber - Lebanese American UniversityYasser Al-Sarraj - Shafallah CenterYoussef Chami - Lebanese American UniversityYasmine Akle - Central Institute of Mining and Fuel ResearchKamal Hirbli - Lebanese American UniversityRita Nemr - Lebanese American UniversityRechdi Ahdab - Lebanese American UniversityDaniel E Platt - IBMAntoine B Abchee - American University of BeirutHatem El-Shanti - Shafallah CenterPierre A Zalloua - Harvard University
- Resource Type
- Journal article
- Publication Details
- Diabetology and metabolic syndrome, Vol.6(1), pp.89-89
- Publisher
- BioMed Central
- DOI
- 10.1186/1758-5996-6-89
- PMID
- 25191526
- PMCID
- PMC4153892
- ISSN
- 1758-5996
- eISSN
- 1758-5996
- Language
- English
- Date published
- 08/21/2014
- Academic Unit
- Stead Family Department of Pediatrics; Medical Genetics and Genomics
- Record Identifier
- 9984353826402771
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